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Showing 1 to 5 of 5 for “"c12-CLA"”.
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Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content
Dairy products are a primary source of c9, t11-CLA, an anti-carcinogenic agent, in the diet of humans. The t10, c12-CLA isomer, typically in trace amounts in bovine milk fat, also may benefit human health. Four cows received abomasal infusions of c9, t11-CLA or t10, c12-CLA to obtain milk fat used …
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Regulation of sterol regulatory element binding protein-1 in bovine mammary epithelial cells
… was conducted to determine the effect of t10, c12-conjugated linoleic acid (CLA) on insulin induced gene-1 (Insig1), an endoplasmic reticulum (ER) protein that anchors SREBP1 and prevents proteolytic activation of SREBP1. MacT cells were treated with increasing levels of t10, c12-CLA. High …
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Conjugated linoleic acid isomers anti-neuroinflammatory effects on activated microglial cells
Conjugated linoleic acid (CLA) isomers display anti-inflammatory effects within the central nervous system (CNS). This research examined how CLA isomers c9,t11 and t10,c12 influence fatty acid (FA) and N-acylethanolamine (NAE) profiles, along with their relationship with the expression of …
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Potentiation of drug-induced cytotoxicity by conjugated linoleic acids (CLA) in in vitro models of drug-resistant cancer
… the effects of conjugated linoleic acids (CLA) and various anticancer drugs on growth of MCF-7 and MCF-7/cis cell lines and to evaluate the effects of co-treatments of CLA and doxorubicin (Dox) on cell growth, intracellular drug accumulation, sphingolipid content and cellular lipid …
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Conjugated Linoleic Acid in the treatment of murine autoimmune glomerulonephritis
Conjugated linoleic acid (CLA) has been shown to reduce inflammation via Peroxisome Proliferator-Activated Receptor (PPAR)-γ in inflammatory disorders such as Crohn's Disease and Inflammatory Bowel Disease. We sought to determine whether CLA isomers would reduce inflammation via PPAR-γ in cultured …