Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"c-myc activation"”.
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Molekulare Genomanalysen des invasiven Mammakarzinoms und Untersuchung des Einflusses chromosomaler Imbalancen auf die Genexpression
… than their ductal counterparts. Evidence of gene activation and inactivation were detected in the form of minimal deviations of gene copy numbers, and amplifications. A linear dependancy of gene copy number was detected for CDH1 (16q22; E-Cadherin) and MYC (8q24; c-myc). Activation through …
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Glucose-6-Phosphatase in Metabolic Disease and Cancer
… show that the oncogenic transcription factor c-Myc potentiates metabolic rewiring and drives lactic acidosis and hyperuricemia in a mouse model of GSD1a. Using metabolic profiling and isotope labeling strategies in both in vivo and cultured cell models of GSD1a, we found enhanced use of both …
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Strategies for Oncogenesis by Avian Leukosis Viruses
… levels of RNA that hybridizes to v-rnyc probe. v-myc is the transforming gene of the rapidly transforming virus MC29. The new poly(A) RNAs found in ALVinduced lymphomas contained myc information and ALV proviruses were found integrated adjacent to c-myc (c-myc is the cellular counterpart of …