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Showing 1 to 2 of 2 for “"c-myc activation"”.

  1. Glucose-6-Phosphatase in Metabolic Disease and Cancer

    … show that the oncogenic transcription factor c-Myc potentiates metabolic rewiring and drives lactic acidosis and hyperuricemia in a mouse model of GSD1a. Using metabolic profiling and isotope labeling strategies in both in vivo and cultured cell models of GSD1a, we found enhanced use of both …

    utswmed Repository record for Glucose-6-Phosphatase in Metabolic Disease and Cancer (opens in a new tab)

  2. Strategies for Oncogenesis by Avian Leukosis Viruses

    … levels of RNA that hybridizes to v-rnyc probe. v-myc is the transforming gene of the rapidly transforming virus MC29. The new poly(A) RNAs found in ALVinduced lymphomas contained myc information and ALV proviruses were found integrated adjacent to c-myc (c-myc is the cellular counterpart of …

    rockefeller Repository record for Strategies for Oncogenesis by Avian Leukosis Viruses (opens in a new tab)