Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 93 for “"c-fos"”.
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Haloperidol-Environment Interaction Modulates Expression of c-Fos Proteins in the Basal Ganglia in Rats
… group showed increased descent latencies. c-Fos immunohistochemistry was used to identify brain regions associated with inverse incentive learning. Expression of c-Fos positive neurons in the nucleus accumbens core and ventral pallidum was significantly lower in the Paired rats than in the …
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Erforschung des Beitrags des MAPK- und STAT-Signalwegs an der EGF-vermittelten Aktivierung der c-fos-Gen-Expression
Das c-fos-Gen enthält eine Vielzahl regulatorischer DNA-Bindestellen in seiner Promotor-Region. Diese Promotor-Elemente sind entscheidend an der spezifischen Antwort zu verschiedenen Umweltreizen, denen Zellen im Körper ausgesetzt sind, beteiligt. Die Stärke der c-fos-Gen-Expression ist abhängig …
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Helicobacter Pylori aktiviert den Transkriptionsfaktor AP-1 über mitogen-aktivierte Proteinkaskaden und induziert die Protoonkogene c-fos und c-jun
… in einer Neusynthese des Protoonkogens c-Fos auf mRNA und Proteinebene. Auch vermag H.pylori in AGS Zellen die MAPK JNK zu aktivieren und konsekutiv die Transaktivierungskapazität von c-Jun durch Phosphorelierung zu erhöhen. <br>Entscheidend hierbei ist, daß nur H.pylori Stämme mit einer …
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TrkB and gene expression
… of genes. This group consisted of: egr1, egr2, c-fos and mGIF/Tieg1. These genes were found to be differentially regulated in the signaling point mutant mice. Although the promoter of mGif/TIEG1 is not yet characterized and also the function of this gene is not completely clear, egr1, egr2 and …
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Die Wirkung von Agrin auf die Genexpression isolierter Maus-Podozyten in Langzeitkultur
… Genexpression für den Wachstumsfaktor c-Fos und den Wachstumsfaktor-Rezeptor Activin A Rezeptor, Typ 1 B nach Agrin-Stimulation zeigen. Ein Einfluss von Activin A und c-Fos auf die strenge Zellzykluskontrolle der Podozyten ist bisher nicht bekannt. Es wäre daher von großem Interesse die …
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Circadian activation of the hypothalamic-pituitary-adrenal axis may affect central, but not peripheral, effect of lithium in conditioned taste aversion learning in rats
… and the HPA axis activation and increased c-Fos expression in both the parabrachial nucleus (PBN) and the nucleus tractus of solitarius (NTS) in a dose dependent manner. However, intracerebroventricular lithium (0.6 M, 5 µl) at night failed to induce CTA or the HPA axis activation, although …
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Über die Beteiligung EGF-Rezeptor-vermittelter Signaltransduktionswege an den tumorpromovierenden Effekten von 2-Acetylaminofluoren, 2-Nitrosofluoren und Phenobarbital in HepG2-Zellen
… der Proteinkinase C (PKC), der Protoonkogene c-FOS und c-JUN in HepG2 Zellen bestimmt. Nur PB hemmte die Expression des EGF-R, wohingegen die PKC, c-FOS und c-JUN nicht beeinflusst wurden. 2-AAF, 2-NOF und PB wirkten konzentrationsabhängig zytotoxisch und antiproliferativ auf HepG2-Zellen. Die …
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Neurochemical and functional characterisation of the Melanin-concentrating hormone system in the rat brain
… physiological stimulation can be mapped using c-Fos immunohistochemistry. In the first experimental design, central administration (icv) of MCH in the rat brain resulted in acute and significant increase of food and water intake, but this animal treatment did not induce a specific c-Fos induction …
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Effects of exogenous and endogenous factors on appetite regulation in broiler chicks and Japanese quail
… arcuate nucleus (ARC) there was an increase in c-Fos immunoreactivity, indicating neuronal activation, in FA-treated chicks. Within the hypothalamus, there was a decrease in mRNA abundance of galanin, ghrelin, melanocortin receptor 3, and pro-opiomelanocortin (POMC), however within the ARC there …
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Anatomical and Physiological Characterization of Striatal Activation of the Cerebral Cortex
… 75 min before mouse perfusion. Second, c-Fos mapping was used to evaluate neuronal activity. C-Fos is an immediate-early gene with activity-dependent protein expression that can be detected by immunostaining. We observed neuronal activity in the motor cortex, striatum, motor thalamus, …
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Consequences of stochastic mrna synthesis in a gene regulatory pathway
… using the serum-mediated induction of c-Fos and c- Jun as a model. c-Fos and c-Jun are transcription factors that together form heterodimers and induce the expression of downstream genes. With the aid of single-molecule fluorescence in situ hybridization for the detection of individual …
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Zwei-Hybrid-Fluoreszenzkreuzkorrelationsspektroskopie : In vivo Charakterisierung von Protein-Protein-Wechselwirkungen im AP-1-System
… Wechselwirkung zwischen den AP-1-Komponenten c-Fos und c-Jun mit der so genannten �Zwei-Hybrid�-Fluoreszenzkreuzkorrelations-spektroskopie in vivo nachgewiesen. Des Weiteren wurden die Mobilität und die Dynamik dieses Komplexes in lebenden Zellen charakterisiert. AP-1 (Aktivator Protein-1) ist …
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Neuroanatomical Maps and Taste Reactivity to Sweet, Umami, and Bitter Taste in the PBN of C57BL/6J Mice
… visualization of the immediate early gene <em>c-fos </em>in PBN neurons. In fact, previous research has indicated stimulation with different taste qualities produces distinctive <em>c-fos </em>patterns in the PBN. For this current research study, my first hypothesis was that since previous …
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Social predispositions and underlying neural mechanisms in chicks (Gallus gallus domesticus)
… staining of the immediate early gene product c-Fos as a neuronal activity marker. In a first behavioural study, visually naïve chicks demonstrated to have an innate preference for visible speed changes, cues of self-propulsion (implying an internal energy source to the moving object). In a …
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Tumor Response TCF-4/β-Catenin Regulatory Elements for Enhancing Cancer Gene Therapies
… enhancer element in combination with a c-fos or carcinoembryonic antigen promoter was tested for its ability to act as a tumor specific regulator of gene expression in a panel of human tumor and normal cell lines. Luciferase reporter assays indicated enhanced activity of the …
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A Behavioral and Anatomical Analysis of Conditioned Taste Aversion in C57BL/6J and DBA/2J Mice
… taste aversion, including the use of c‑Fos as a method of labeling neurons that respond to a specified behavior. </p> <p>The use of inbred strains of mice, specifically the common strains C57BL/6J (B6) and DBA/2J (D2), allows for the investigation of phenotypic variation and specific …
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Roles of dopamine D1 and D2, opioid and glutamate NMDA receptor signaling in the acquisition and expression of fat- and glucose-conditioned flavor preferences in rats and c-Fos analysis of the dopamine mesotelencephalic and nigrostriatal pathways following intake of sugars and fats in rats
… NAc core, AMY, mPFc and CPu) simultaneously for fos-like immunoreactivity (FLI) following oral ingestion of CO (f/f and f/n), glucose (f/f and f/n), fructose (f/f) and three controls (water, saccharin and xanthan gum). CO, which was isocaloric to fructose and glucose, elicited significantly …
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Changes in macrophage functions and gene expression during tumor growth
… and TBH Mφ. The proto-oncogenes c-myb, c-myc, c-fos, and c-fms are constitutively expressed in TBH Mφ, while normal host M@ express c-fos and c-fms but at lower levels. Adherence suppresses the expression of the proto-oncogenes c-myb, c-myc, and c-fms in TBH Mφ, while inducing c-fos and c-fms in …
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