Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"c-erbB2"”.
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Charakterisierung von Schlüsselproteinen der Signaltransduktion (EGF-R, c-erbB2, Hsp90) in humanen Tumorxenografts mittels Gewebemikroarray
… der Signaltransduktion (EGF-R, c-erbB2, Hsp90) wurden in dieser Arbeit untersucht. Überexpression dieser Proteine in Tumoren geht mit schlechter Prognose für die Patienten einher. EGF-R und c-erbB2 sind deshalb interessante Targets für neue molekulare Tumortherapien. Spezifische …
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Molecular factors influencing epithelial-mesenchymal transition in breast cancer
… from the oncogenic receptor tyrosine kinase c-erbB2 (HER2), frequently overexpressed in mammary cancers, induces EMT. In this system, c-erbB2-induced EMT was significantly delayed by high cell-density and cell-cell-dissociation occurred before downregulation of the epithelial adhesion molecule …
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Molekulare Genomanalysen des invasiven Mammakarzinoms und Untersuchung des Einflusses chromosomaler Imbalancen auf die Genexpression
… factor receptors EGFR (7p12; EGF receptor) and ERBB2 (17q11.2-12; c-erbB2). Fourteen candidate genes for mammary tumorigenesis were identified, whose involvement in the malignant processes of breast cancers are only partly understood and still remain the targets of further investigations.
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Potentiation of drug-induced cytotoxicity by conjugated linoleic acids (CLA) in in vitro models of drug-resistant cancer
… in down-regulation of Her2/neu coded p185 c-erbB2/c-neu oncoprotein expression. Eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) resulted in similar down-regulation of this protein in the A10p10p cell line. Fatty acid composition of MDA and A10p10p cells was analysed by gas …