Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"c/ebpbeta"”.
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Analysis of the Role of the Transcription Factor-C/ebpbeta in Implantation
… previously identified the transcription factor C/EBPbeta as a target of steroid hormone regulation in the uterus. The uteri of C/EBPbeta-null mice failed to undergo decidualization, indicating a critical role of this transcription factor in this process. In the present study, analyses of …
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Understanding C/EBPbeta LAP/LIP Transcriptional and Adipogenic Potential Through Regulation by HDAC1 and GCN5
The CCAAT/Enhancer Binding Protein Beta (C/EBPβ) is part of the leucine zipper family of transcription factors and is involved in a myriad of processes including cellular proliferation and differentiation. C/EBPβ is expressed as three isoforms (LAP*, LAP, LIP), translated from a single mRNA by a …
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Analysis of the Role of the Transcription Factor C/EBPbeta in Controlling Uterine Functions During Early Pregnancy
… factor, CCAAT Enhancer Binding Protein Beta (C/EBPbeta) as a prominent target of estrogen and progesterone signaling in the uterus. The development of a C/EBPbeta-null mouse model, which is infertile, presented us with an opportunity to analyze the role of this molecule in uterine function. We …
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In Vivo Studies on the Transcriptional and Posttranslational Regulation of the CCAAT/Enhancer Binding Protein Beta
The transcription factor C/EBPbeta gene has CREB responsive elements (CRE) in its promoter, and its transcription is regulated by CREB during adipogenesis. We have generated a mouse line with a deletion of the CRE elements on the C/EBPbeta promoter and stusied the role of these elements in …
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Analysis of the Transcriptional Regulation and Bidirectional Nature Of the Promoter of the p53 Tumor Suppressor Gene
… two transcription factors, RBP-Jkappa and C/EBPbeta-2, which bind to the p53 promoter and regulate p53 transcription. The results indicate that the two proteins bind to the -972/-953 region on the p53 promoter. RBP-Jkappa serves to repress p53 transcription during growth arrest, while …
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Regulation of the potential tumorsuppressor gene mad1 by G-CSF
… constitutively, C/EBP proteins, especially C/EBPbeta, appear to play major roles in the induction of the mad1 gene in response to G-CSF. Fourth, STAT3 is implicated in the regulation of mad1 expression in an indirect way, suggesting a new cooperative mechanism with C/EBP. Finally, regarding …
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Role of Cyclin-Dependent Kinase Inhibitors in Estrogen Regulation of Adipogenesis
… to increase in transcriptional factors like C/EBPbeta, C/EBPalpha, PPARgamma and Glut4. Wild-type (WT) mouse embryonic fibroblast (MEFs) had increased mitotic clonal expansion (MCE) due to lack of estrogen but this was not seen in p27KO MEFs, that showed that the effects due to these two …