Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"burst firing"”.
-
Top-down and bottom-up interactions for cortical bursting
High-frequency burst firing occurs throughout the mammalian cortex in vivo, yet both the underlying mechanisms and functional roles of bursts are unclear. Burst firing in brain slices is strongly modulated by the activity of apical dendrites, which branch extensively in layer 1 (L1) and receive …
-
Mechanisms of neuronal integration in adrenomedullary sympathetic preganglionic neurons.
… T-type calcium channels that serve to facilitate burst firing. 75% of AD-SPN exhibited evidence of electrotonic coupling, indicated by characteristic oscillations in membrane potential and confirmed with dual recordings from electrotonically coupled AD-SPN. Electrotonic coupling promoted …
-
Effect of dopamine on synchronous neuronal oscillations in the globus pallidus-subthalamic nucleus network
… a pacemaker driving regenerative synchronous bursting activity. In order to test whether this activity can be sustained in vitro a 20o parasagittal slice of mouse midbrain was developed which preserved functional connectivity between the STN and GP. Mouse STN and GP cells were characterised …
-
Modificazioni neuronali nella via abenulo-mesencefalica durante l’astinenza da Δ9-tetraidrocannabinolo
… withdrawal produced a marked decrease in the firing rate and burst firing of VTA DA neurons. We then investigated the inhibitory contribution from RMTg afferents to VTA DA neurons. As expected, RMTg electrical stimulation elicited a complete suppression of spontaneous activity in approximately …
-
Functions of GluN2D-containing NMDA receptors in dopamine neurons of the substantia nigra pars compacta
… in PD these afferents display a higher frequency firing, as well as increased burst firing, which could cause increased excitatory activity in SNc-DA neurons. NMDA receptors (NMDARs) bind the excitatory neurotransmitter glutamate, and are essential for learning and memory. In SNc-DA neurons, …
-
PIP2 Modulation of Afterhyperpolarizations in Magnocellular Supraoptic Neurons
… stimuli. These cells exhibit unique phasic and burst firing patterns to release these peptides into the circulatory system where they primarily control milk ejection and parturition (OT) as well as salt-water balance and vasoconstriction (VP). This firing is underlain by intrinsic ionic …
-
Unique Response Properties and GABA<sub>A</sub> Receptor Function in Medial Geniculate Body Neurons of Young and Aged Fischer Brown Norway Rats
… resting membrane potential, reduced evoked firing rates and induced a transition from tonic to burst firing mode. In aged MGB neurons there was a significant 50.4% reduction in GABA<sub>A</sub>R-mediated tonic Cl- current. Synaptic GABA<sub>A</sub>R inhibition appeared differentially …
-
Simulating the Affects of Glutamatergic Afferents on the Firing Pattern of Midbrain Dopamine Neurons
… input is roughly balanced, both single spike firing and bursting can be observed. Simulated SK channel block strengthens the correlation between pattern and rate and increases the number of spikes fired in bursts by increasing the spikes per burst. A simulated doubling of the AMPA/NMDA ratio …
-
Molecular Substrates And Neuronal Network Subserving Audiogenic Kindling In Genetically Epilepsy-Prone Rats
… CeA a significantly greater increase in neuronal firing in PAG was seen in AGS kindled GEPR-9s as compared to non-kindled GEPR-9s. PAG neurons in AGS kindled GEPR-9s showed a precipitous increase in responses to CeA stimulation. The PAG neurons also displayed significantly increased responsiveness …