Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"bulk cancer"”.
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Transient Metabolic Alterations Induced by Chemotherapeutics in Cancer Persisters
… drug tolerance has been a major challenge in cancer therapy. Recent evidence has revealed the existence of slow-cycling persister cells that survive drug treatments and give rise to multi-drug tolerant mutants in cancer. The mechanisms associated with persister phenotypes are highly diverse …
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DEVELOPMENT OF A BIOINFORMATICS FRAMEWORK TO IDENTIFY CELL SUBPOPULATIONS FROM BULK TRANSCRIPTIONAL DATA
… cells and tissue composition. Nevertheless, in bulk transcriptional profiling, each sample is evaluated without considering the presence of multiple subpopulations. This limitation might be extremely critical when analyzing bulk gene expression profiles of cancer samples, where dissecting the …