Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 63 for “"breast cancer treatment"”.
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Echogenic Liposomes For Nitric Oxide Delivery and Breast Cancer Treatment
… as a carrier for drugs and antitumor agents in cancer chemotherapy. Echogenic liposomes (ELIP) have the potential to entrap air or bioactive gas to enhance acoustic reflectivity in ultrasound and are used as a contrast agent. The innovative part of this study is based on a novel concept to …
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Physical Activity Predicts Physical Function in Women Undergoing Breast Cancer Treatment
The American Cancer Society estimates that 1 in 8 women will be diagnosed with breast cancer in her lifetime. Due to 5-year survival rates of 89.7%, it is important to examine factors that impact physical function over the course of cancer treatment. Purpose: To prospectively analyze changes in …
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The Effect of Dietary Genistein on Breast Cancer Treatment and Metastasis
… study, dietary genistein was shown to promote breast cancer metastasis to lungs in athymic mice. The results from these studies suggest that the consumption of dietary supplements containing genistein may not be safe to breast cancer survivors. In our third study, we evaluated three metastasis …
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Evaluation of Decision Support Aids for Early Stage Breast Cancer Treatment among Rural Women
While more than two decades ago breast conservation therapy (BCT) was shown to be equivalent to mastectomy in terms of survival, its acceptance has not been proportional to the number of candidates eligible for BCT, especially in rural areas. Decision support aids can be utilized to streamline …
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The Use of Oncology Electronic Health Record Databases to Assess the Effectiveness of Breast Cancer Treatment
… that reflect real-world practice patterns and treatment adherence. Historically, pharmacoepidemiology research in the oncology setting has been limited, mainly due to poor capture of important confounding factors in real-world data sources (e.g., tumor grade, histology, and location, laboratory …
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The impact of having intellectual or developmental disabilities on breast cancer treatment: A convergent mixed-methods study
… (IDD) are more likely to die with and from breast cancer. Exploring how people living with IDD receive or do not receive guideline-recommended treatment for breast cancer can help inform strategies for improving patient-centred care. Methods: This mixed methods project includes three …
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Utilization of Proton Pump Inhibitors in Combination Regimen for Breast Cancer Treatment by Targeting Fatty Acid Synthase
… associated with poor prognosis and recurrence in cancer patients. In addition, it has also been found that overexpression of FASN causes resistance to DNA-damaging treatments by up-regulating the non-homologous end joining (NHEJ) repair of DNA double-strand break. Proton pump inhibitors (PPIs), …
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Assembly, characterization and evaluation of a 3rd generation nanoparticle based drug carrier for metastatic breast cancer treatment
Cancer is one of the leading causes of death in the world. For women in the U.S. and the European countries, breast cancer is the most common type and it continuously threatens the lives of the patients and causes huge economic losses. Chemotherapy and endocrine therapy are the common treatments …
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Understanding the Primary Health Care Needs and Current Care Guidelines for Women Following Breast Cancer Treatment: a Scoping Review and Validation Study
… the primary health care needs of women following treatment for breast cancer. Methods: Based on an extensive scoping review of the literature, research findings regarding the complications of breast cancer treatments and corresponding primary care interventions were synthesized. Additionally, …
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Investigation of chemoresistant mechanisms in triple negative breast cancer cell lines and development of a nano-enabled Disulfiram for breast cancer treatment
Cancer a global epidemic is a major cause of morbidity and mortality affecting populations in all nations and regions. Breast cancer (BC) is the second most common cancer in the world and the most fatal malignancy affecting women both in the developed and developing countries. Even with the …
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Exploring the association between gene sequence polymorphisms within the angiogenesis and extracellular matrix regulatory pathways and shoulder pain and disability following breast cancer treatment
… pain and disability are common sequelae of breast cancer treatment in women, with an understated negative impact on the quality of life of affected individuals and a poorly characterised aetiology. A better understanding of the aetiology of shoulder pain and disability in breast cancer …
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Understanding the Impact of Hobby Participation on Quality of Life During Cancer Treatment
… engagement in life-threatening illness and cancer. The aim of this study is to explore the role of regular hobby participation on QoL with regards to finding purpose and meaning making, increased coping skills, and social support through hobby participation during breast cancer treatment. …
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Understanding The Role of Arglu1 In Interferon Signaling Activation In Breast Cancer
<p>In the U.S., the highest number of new cancer cases belongs to breast cancer in women, and this cancer also bears the second-highest death rate in women. Despite significant progress in breast cancer treatment that has been made in the past several decades, innovative and efficient therapies are …
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Management of breast cancer in the Medicaid population
Breast cancer is the second most comcancer and the second leading cause of cancer-related death among women. The current project examined some key issues important for effective breast cancer management in the Medicaid population. Medicaid is one the largest healthcare insurance systems in the US …
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Next generation near infrared (NIR) and shortwave infrared (SWIR) wearables for breast cancer imaging
Neoadjuvant chemotherapy (NAC) is a common breast cancer treatment that involves administering chemotherapy for 3-6 months prior to surgery. This treatment enables more breast-conserving surgeries and even allows for the omission of surgery in some cases. However, about 31% of patients receiving …
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The Effects of 1,25-Dihydroxyvitamin D3, Docosahexaenoic Acid and 5-Fluorouracil on Human Breast Cancer Cells
… antiproliferative effects on a variety of human cancers, including breast cancer. Studies have shown that a combination approach to cancer treatment is more effective than any one treatment administered alone. In this study, human mammary epithelial cells from the MCF-7 cell line were treated …
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Estrogen Receptor -Dependent and Estrogen Receptor-Independent Pathways for Tamoxifen and 4-Hydroxytamoxifen-Induced Programmed Cell Death
One of the most common methods of breast cancer treatment is antiestrogen treatment. The therapeutic efficacy of the selective estrogen receptor modulator tamoxifen (TAM) in cancer therapy is thought to arise from its ability to compete with estrogens for binding to the ER. We show that TAM and its …
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Women's lived experiences of the breast cancer trajectory: the waiting period for treatment and the impacts on feminine identity
Breast cancer, according to research, is diagnosed in approximately one in every twenty-nine women in South Africa. Differences in gender, race and class produce disparities in health care, subjecting lower class women to lengthy waiting periods between diagnosis and treatment. Present research …
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Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study
Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013 to 2017: A single centre study Background: Breast cancer is the leading cause of cancer- related deaths globally, and the commonest cancer in women under 40 years. There is …
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Hypoxia and Hypoxia-Inducible Factors in Normal and Malignant Breast Epithelium
Breast cancer treatment is based on tumor and patient related factors such as tumor stage, grade, hormonal status, HER2 status, patient age, and family history to name a few. It is today widely acknowledged that hypoxia and hypoxia-inducible factors (HIF:s) contribute to tumor progression. We …
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