Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"breakage-fusion-bridge cycle"”.
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Repetitive Sequences Drive Rapid Adaptation in Candida albicans
… antifungal drug, due to successive rounds of the breakage-fusion-bridge cycle and homologous repair. Importantly, we describe how removal from antifungal drug promotes rapid loss of the complex CNVs, resulting in the ancestral genotype and azole antifungal drug susceptibility These findings, while …
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Mechanisms and Consequences of Chromosomal Instability in Malignant tumours
… which could explain the fact that anaphase bridges and multipolar mitoses were only observed in these tumour elements. Because of breakage-fusion-bridge cycles, chromosomal instability is associated with karyotypes with extensive structural chromosomal rearrangements. By applying a …