Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"brain-blood barrier"”.
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Cancer Proliferation at the Brain Metastatic Site: A Proteomic Exploration of Inter-Cellular Cross-talk Sustained by Cell-membrane/Secretome Interactions
Brain metastasis of breast cancer is one of the leading causes of mortality in patients suffering from cancer. The unique structure and components of the brain microenvironment, including the brain-blood barrier and the immune-suppressive environment, present significant clinical challenges to …
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Effects of Penfluridol On Integrin-Fak Signaling and Tumor Cell Killing In Combination With Oncolytic Hsv In Glioblastoma
… are limited in their penetration of the blood brain barrier, we investigated the use of Penfluridol, an antipsychotic drug known to attenuate integrin expression at a transcriptional level, in combination with oncolytic herpes simplex I virus (oHSV) in a glioblastoma model. We examined …