Global ETD Search
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Showing 1 to 18 of 18 for “"botulism"”.
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A Clinico-Pathologic Study of Botulism in Ring-Necked Pheasants
Toxins were produced from 6 strains of Cl. Botulinum, 2 of which killed pheasants. Inoculated birds were observed and a description of the progression of signs of the disease is given. Juvenile pheasants were inoculated with Types A and C toxin intramuscularly and were given the toxin orally. These …
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STOMACH CONTENT ANALYSIS OF BOTULISM-AFFECTED BIRDS IN LAKE MICHIGAN
<p>Avian botulism type E has caused large-scale bird and fish die-offs on the Great Lakes annually since 1998, and continues to threaten breeding and migratory waterbirds in the region. From 2010 to 2012, several northern Lake Michigan beaches were monitored for avian mortalities by National Park …
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Botulism and Its Ophthalmic Lesions as Determined by Research With the Toxin of Clostridium Botulinum
The subject of botulism has never received due consideration or study on the part of ophthalmologists, although recognition of the syndrome which involves the globe and its adnexa, is paramount in the clinical diagnosis of the disease. Strange to say most of the data relative to the ocular findings …
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Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinum
… growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification control for C. botulinum types A, B and E was developed. The method was used to diagnose the first case of wound botulism in an injecting drug user in Sweden, which was also …
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An Avian Botulism Epizootic Affecting a Nesting Site Population of Presbyornis : on a Carbonate Mudflat Shoreline of Eocene Fossil Lake
… calcimicrite.</p> <p>Analogous modem avian botulism epizootics are often preceded by a mass mortality of aquatic invertebrates, which are exposed and killed by rapid shoreline regression. Many mechanisms have been proposed for mass mortality of waterfowl. The evidence from this site is most …
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ANALYSIS OF PROTEASE ACTIVITY USING MEMBRANE- COATED BIOMIMETIC MICROSPHERES
… to the severe neuroparalytic illness known as botulism, which is characterized by flaccid paralysis, respiratory failure, and death. BoNTs are the most acutely toxic substances on the planet, so detection at physiologically relevant concentrations is difficult. Because current treatments for …
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ETHICAL CONSIDERATIONS OF THE USE OF INVESTIGATIONAL NEW DRUGS DURING THE GULF WAR
… new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the Interim Rule, which permitted the use of investigational new drugs when consent could …
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Development of a cargo delivery system and inhibition studies focused on clostridium difficile toxin a
… infections such as diphtheria, anthrax, botulism, and tentanus. In the case of enzymatic exotoxins, disease arises from cytotoxic proteins, and cytotoxicity is acheived only after cell entry. This intrinsic mechanism for cell entry is intriguing from research and medical views. Along with …
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Morphogenesis of the Bacillus Anthracis Spore
… diseases such as tetanus, anthrax, gas gangrene, botulism, and diarrhea. Spore-forming bacteria differentiate into spores in response to stresses (especially starvation) in a multi-stage developmental pathway involving the coordinated expression of hundreds of genes and the formation of …
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Hydrogels for Biomacromolecule Immobilization and Sensing
… were responsive to alpha-chymotrypsin (CKYC) and botulism neurotoxin (CSNKTRIDEANQRATK{Nle}LC) were successfully synthesized and copolymerized into polyacrylamide hydrogel networks. When exposed to buffered solutions that contain their sequence specific protease, the hydrogels were completely …
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Exploring new chemical entities from traditional medicine: Docking, synthesis and specific bioactivities
… for treating diseases with symptoms similar to botulism. The phytochemicals of these plants were studied by docking into the catalytic domain of BoNT/A. From the docking results, thirty-one compounds and their analogues were identified and tested in vitro using liquid chromatography-based …
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Valoración energética del residuo avícola, impacto económico-ambiental y análisis experimental en Europa de la reducción de amoniaco en explotaciones avícolas mediante compuesto encimático
… agua (91/676/CEE) y el incremento de casos de botulismo en países como Irlanda han hecho necesaria la búsqueda de soluciones alternativas a la gestión de la gallinaza, residuo generado en el sector avícola, que tradicionalmente se ha empleado como fertilizante. El uso de este residuo como …
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Local Administration of Botulinum Toxin Type-B in the External Anal Sphincter of Horses Produces Transient Reduction of Peak Anal Pressure
Toxins produced by the Gram-positive bacteria Clostridium botulinum cause transient chemodenervation of mammalian muscle. The toxin binds to specific proteins within cholinergic presynaptic nerve terminals which regulate the release of acetylcholine in the synaptic space resulting is loss of muscle …
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Analysis of TpeL secretion in Clostridium perfringens
… to treat and often deadly, including colitis, botulism, tetanus and gas gangrene. These diseases are caused by the secretion of specific toxins, though current treatments do little to nullify these toxins and better therapeutics are urgently needed. The development of such treatments is …
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Enfermedades de la placa neuromuscular
En este capítulo se describen las enfermedades de la placa neuromuscular, su epidemiología, hallazgos clínicos, métodos diagnósticos y tratamiento de cada una de ellas
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The Comparison of Airway Responses of Normal Horses Fed Round Bale versus Square Bale Hay
Background – Feeding horses round bale hay (RBH) has been associated with airway inflammation. The purpose of this study was to determine if horses fed RBH for a 6-week period demonstrated more evidence of airway inflammation than horses fed square bale hay (SBH) of comparable quality. Hypothesis - …