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Showing 1 to 20 of 105 for “"bone resorption"”.
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Reduced order modelling of bone resorption and formation.
The bone remodelling process, performed by the Bone Multicellular Unit (BMU) is a key multi-hierarchically regulated process, which provides and supports various functionality of bone tissue. It is also plays a critical role in bone disorders, as well as bone tissue healing following damage. …
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Novel Molecules that Regulate Bone Formation and Bone Resorption
… is a disease characterized by decreased bone mass and microarchitectural deterioration of bone. Bone loss occurs when the increased bone resorption that occurs with age is not compensated by a corresponding increase in bone formation. Therefore, understanding the mechanisms which regulate …
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Developing New Chemotherapeutic Agents Against Bone Resorption and Parasitic Diseases Through Computer -Aided Drug Design
Using the above mentioned 3D-QSAR methods we have developed predictive models of the inhibition of human farnesyl pyrophosphate synthase (FPPS), important for osteoclast function and survival as well as Trypanosoma brucei FPPS, soluble vacuolar pyrophosphatase and phosphoglycerate kinase, all …
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The Physiological Effects of The Dietary Calcium - to - Phosphorus Ratio on Bone Resorption and Magnesium Metabolism in Adult Rats
Made available in DSpace on 2015-05-12T21:45:24Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7020918.PDF: 5693829 bytes, checksum: 856f3cab1905225955e200c72ac6deb7 (MD5) Previous issue date: 1970
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CLINICAL AND RADIOGRAPHIC EVALUATION OF MARGINAL BONE RESORPTION OF ONE-PIECE IMPLANTS IN FULL ARCH REHABILITATIONS WITH FULL DIGITAL APPROACH: A PROSPECTIVE COHORT STUDY.
… the study primarily evaluates the marginal bone stability and the long-term performance of monophasic implants subjected to immediate loading. These implants, characterized by the elimination of the abutment-fixture interface, aim to enhance mechanical stability and minimize the risks of …
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The Effect of Low Dose, Long Term Calcium Infusions on Bone Metabolism
… studies have recently shed some light on the bone formation rates in various disease states. Using Ca-45, Bauer et ale (1), in Sweden, and Heaney (2), at the National Institute of Health, devised a method of determining rate of calcium deposition in various diseases. By their technique …
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Studies of the role of nf-κb in controlling osteoclast differentiation and bone loss
Increased osteoclast (OC) bone resorption and/or decreased osteoblast (OB) bone formation contribute to bone loss in osteoporosis and rheumatoid arthritis (RA). Findings of the basic and translational research presented in this thesis demonstrate a number of mechanisms by which cytokine-induced …
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An Investigation of the Effects of a Dietary Calcium and Vitamin D Supplement on the Resorption of the Alveolar Ridge of the Jaw in Immediate Denture Patients
… of a calcium and vitamin D supplement on the resorption of alveolar bone following teeth extractions in human subjects. Studies have been cited which indicate a positive relationship between adequacy of calcium intake and maintenance of the bones of the jaw.</p> <p>In this investigation, …
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Association of genotype with bone metabolism, skeletal adaptation and stress fracture injury occurrence
Positive changes in bone metabolism, structural characteristics, size and mass are commonly associated with weight-bearing exercise. Despite this, negative effects of exercise on bone phenotypes, such as stress fracture injuries have been reported. Little is known about the extent of the genetic …
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An Improved Understanding of Bisphosphonates Through Computational Techniques
… are currently used to treat human bone resorption disorders. In recent years, these compounds have been shown to have additional biological properties, such as the ability to inhibit the growth of parasite cells and the ability to stimulate human gammadelta T cells. We have used …
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Étude de l’expression et du rôle du ligand du co-stimulateur inductible des cellules T (ICOSL) dans les ostéoclastes humains
When cancer cells metastasize to bone, they interact in the bone microenvironment with bone cells and immune cells present in the adjacent bone marrow. Osteoclasts, which degrade the bone matrix, express costimulatory molecules on their surface, like antigen-presenting cells, which enable them to …
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ΣΥΜΒΟΛΗ ΤΟΥ ΑΚΤΙΝΟΛΟΓΙΚΟΥ ΕΛΕΓΧΟΥ ΣΤΗΝ ΕΚΤΙΜΗΣΗ ΤΗΣ ΝΕΦΡΙΚΗΣ ΟΣΤΕΟΔΥΣΤΡΟΦΙΑΣ
… MAGNIFICATION FOR EARLIER DETECTION OF MINIMAL BONE RESORPTION. THE SKELETAL SURVEY INCLUDED VIEWS OF THE THORAX, LATERAL SKULL, LATERAL THORACIC AND LUMPAR SPINE, PELVIS AND THE RIGHT FEMORAL NECK. SKELETAL SURVEY (BONES OTHER THAN HANDS) SHOWED BONE CHANGES IN 32%. THE USE OF FINE DETAIL …
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The Effects of Low Energy Availability and High-Impact Exercise on Bone and Body Composition
… laboratory research has shown suppression of bone formation biomarkers with accelerated rates of bone resorption after only three to five days of LEA in active females. Correcting LEA by increasing EI or decreasing exercise energy expenditure (EEE) may not be feasible for all athletes and …
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The Role of Claudins in Bone Metabolism
… problem in the U.S., is characterized by low bone mass and structural deterioration of bone tissue. Since the imbalance between bone formation and bone resorption during bone remodeling has been documented to be a major factor in the pathogenesis of osteoporosis, it is crucial to identify …
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DIFFERENT TECHNIQUES FOR DENTAL IMPLANTS SITE PREPARATION: A CONTROLLED CLINICAL TRIAL
… could lead to a significantly lower marginal bone resorption as compared to another protocol (“Straight drilling sequence”) at 1-year follow-up. The secondary aims were to evaluate if the tested protocol (Step drilling sequence) could modify the clinical and/or patient-centered variables We …
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The Effect of Long Term High Protein Induced Calciuria on Calcium Metabolism and Bone Status in Adult Rats
… to either increased absorption, increased bone resorption or both. A 20 week study was conducted to determine long-term effects of various protein sources on calcium metabolism and bone status of 500 g male rats "deep-labelled" with ('45)Ca. Controls were fed diets containing 6% protein as …
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Characterization Of The Skeletal Phenotype In Idua-W392X Knock-In Mice: Bone Metabolism Biomarkers
… and short stature. Skeletal biomarkers of bone formation and bone resorption were compared in wild-type, heterozygous, and IDUAW392X mice. To investigate osteoblast activity, levels of the bone formation marker Procollagen type I N-terminal propeptide (PINP) were evaluated. To investigate …
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