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Showing 1 to 20 of 193 for “"bloodstream"”.
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Infection Control: Reducing Hospital Acquired Central Line Bloodstream Infections
… Makic, 2013). It’s estimated that each neonatal bloodstream infection costs about $35,000 and adds about two weeks to a baby’s hospital stay (Akron's Children Hospital, 2015). This project was formulated to reduce the incidence of central line blood stream infections in the neonatal population. …
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Digital amplification for pathogen detection in bloodstream infections from whole blood
… is essential for control and treatment of bloodstream infections. Sepsis, a diagnostic challenge of blood stream infections, causes thousands of deaths each year. The gold standard for detection and identification of microorganisms is blood culture, which can take up to 5 days to yield a …
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Understanding the composition and function of the flagellar groove in bloodstream form Trypanosoma brucei
… tsetse fly. A characteristic feature of the bloodstream from of T. brucei is the flagellum, which is laterally attached to the side of the cell body and is not disassembled during the cell cycle. Instead, a new flagellum is formed alongside the old flagellum, with the distal tip of the new …
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Klebsiella pneumoniae bloodstream infections in hospitalised children at Red Cross War Memorial Children's Hospital : 2006 - 2011
… pneumoniae (KP) is a significant paediatric bloodstream pathogen in children. There is little data about KP in South African children. The focus for the present study was to address this knowledge gap. Methods: This study addressed a retrospective case notes review on bloodstream Klebsiella …
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Most Effective Nursing Interventions to Prevent Central Line-Associated Bloodstream Infections: A Critical Review of the Literature
… by the CDC include central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), ventilator associated pneumonia (VAP), surgical site infections (SSIs), and other infections caused by the bacterium Clostridium difficile. HAIs are among the …
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Empowering Patients with Central Venous Catheters: Utilizing Evidence-Based Video-Assisted Education to Reduce Central Line-Associated Bloodstream Infections
… setting in which Central Line-Associated Bloodstream Infection (CLABSI) rates were rising. Pediatric oncology patients confer the highest risk of developing CLABSIs due to long-term CVC access, neutropenic effects of treatment regimens, and constant fluctuations between inpatient, …
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Genetic and phenotypic diversity of bloodstream associated Staphylococcus epidermidis isolates obtained from private and public hospitals in South Africa
… is a commensal bacterium commonly implicated in bloodstream infections. Most S. epidermidis infections are acquired in hospitals and are associated with the use of medical devices. In contrast to its more virulent relative Staphylococcus aureus, S. epidermidis is often overlooked and regarded as …
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Candida bloodstream infection among children hospitalized in three public sector hospitals in the Metro West region of Cape Town, South Africa
Introduction Candida bloodstream infection (BSI) causes appreciable mortality in children. There are few studies describing the epidemiology of Candida BSI in children living in the Western Cape province of South Africa. Methods A retrospective descriptive study was conducted at three public sector …
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A ten-year review of ESBL and non-ESBL Escherichia Coli Bloodstream infections among children at a tertiary referral hospital in South Africa
Introduction: Bloodstream infection (BSI) is an important cause of morbidity and mortality in children (1). There are few descriptions of Escherichia coli (E. coli) BSI in children, particularly in Africa, yet E. coli is increasing in importance as a cause of antibiotic-resistant infection in …
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Defining the Aetiology and Antimicrobial Susceptibility Patterns of the Predominant Bacteria Associated with Bloodstream Infections at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam
Bloodstream infections (BSI) are among the most common critical diseases that require intensive care and continuous surveillance. According to many multinational antimicrobial resistance surveillance schemes, Asia represents a substantial reservoir of clinically relevant antimicrobial resistant …
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Regulation of Intracellular pH and Plasma Membrane Potential in Trypanosoma Cruzi and Trypanosoma Brucei
… different stages. The trypomastigote (mammalian bloodstream) stage was found to be highly conductive to cations and there was a significant contribution to its DeltaPsi from a ouabain sensitive Na+/K+-ATPase. The epimastigote or insect stage was found to have a low conductance for cations and a …
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Antibody-modified conduits for extracorporeal selective cytokine filtration in sepsis
… year and occurs when microorganisms enter the bloodstream of an infected host. The presence of microorganisms in the bloodstream triggers the body to produce many inflammatory proteins, known as cytokines, that cause damage to blood vessels and vital organs. This leads to capillary leak, …
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Investigating Pulmonary Immune Responses that Detect and Counteract Gram-negative Bacterial Infections
… often leads to pathogens spreading into the bloodstream. In the airways, Gram-negative bacteria produce biofilms through exopolysaccharide (EPS) that provides microbial protection; however, the impact of EPS on detection remains uncertain. Using genome-engineered P. aeruginosa strains, we …
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Preventing and Reducing CLABSI with Daily 2% CHG Wipes
… project aims to decrease central line associated bloodstream infections in pediatric patients my microsystem hospital. The process begins re-enforcing daily CHG (2% Chlorhexidine Gluconate) wipes to 100% compliance rates on our patients with central lines tailored to their age and body weights. …
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Development and evaluation of novel antimicrobial solutions against biofilms and planktonic microbial growth
… a direct route for medical support into the bloodstream. However, when CVCs become colonized by microorganisms, this direct route into the bloodstream can often result in catheter related bloodstream infections (CRBSIs). These infections can be enormously costly,i ncreasing hospitalization …
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Sporopollenin exines as a novel drug delivery system
… as pollen, spores and starch migrate into the bloodstream following ingestion by a process termed 'Persorption'. Such findings intrigued many researchers but the phenomenon has not been unanimously accepted. This research is a body of evidence giving unequivocal confirmation that spores of …
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The Effects of Polysomal mRNA Association and Cap Methylation on Gene Expression in <i>Trypanosoma brucei</i>
… brucei survival between procyclic (vector) and bloodstream (mammal) forms necessitate different molecular processes and therefore changes in protein expression. Transcriptional regulation is unusual in T. brucei because the arrangement of genes is polycistronic; however, genes which are …
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Mitochondrial ATP production and energy-buffering in the human pathogen Trypanosoma brucei
… proteomic analysis of mitochondria in both bloodstream form and procyclic form T. brucei were performed. The preliminary results showed that many enzymes required for TCA cycle, lipid metabolism, amino acid metabolism, nucleotide metabolism exist in both bloodstream form and procyclic form …
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Investigation of the interactions between Trypanosoma congolense invariant surface glycoproteins and components of the mammalian immune system
… upregulated in the mammalian life stage (bloodstream form), supporting the hypothesis that these proteins may function as receptors for ligands in the mammalian host. Selected *T. congolense* ISGs were produced as recombinant proteins using bacterial and mammalian expression systems. …
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