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Showing 1 to 5 of 5 for “"blood substitute"”.
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Total gene synthesis, bacterial expression and functional characterization of a recombinant human hemoglobin: Progress towards a blood substitute
To better understand the role of specific residues of hemoglobin in allosteric function, cooperative interactions, ligand discrimination and protein-protein recognition, a genetic handle is required. The use of total gene synthesis alleviates some of the laborious procedures associated with …
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The Effects of Hemoglobin-Based Oxygen Carriers On Mean Arterial Pressure, Arteriolar Diameter, and Nitric Oxide in the Microcirculation
In the US today, blood transfusion is safer than ever. Nevertheless, the century-old quest for a suitable blood substitute persists. The elimination of unwanted side effects, especially transfusion-transmitted diseases, the problems and high cost factor involved in collecting and storing human …
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Optical fibre-based minimally-invasive blood glucose monitoring system.
… diabetes can be controlled by tightly monitoring blood glucose levels. Several methods to accomplish this have been proposed over the years. In this thesis, a thorough literature and patent review revealed that blood glucose monitors (BGMs) based on amperometry are one of the most common …
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Effekte stromafreier Hämoglobinlösungen auf die Mikrozirkulation im quergestreiften Rückenhautmuskel beim Hamster
… there was pursuit of developing oxygen carrying blood substitutes, but the breakthrough of stroma free hemoglobin solutions has failed due to different issues such as nephrotoxicity, systemic activation of complement cascade, vasoconstriction and other side effects. To prove the in vivo safety …
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Zero length crosslinking of bovine carbonic anhydrase II and chondroitin-4-sulfate
… in this work may be of use as an artificial blood substitute designed to transport CO2 molecules in vivo.