Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 80 for “"blood stream"”.
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Blood stream infections in oncology patients at Red Cross War Memorial Children's Hospital, Cape Town
… There is paucity of data on the epidemiology of bloodstream infection (BSI) in sub-Saharan Africa. To address this knowledge gap, the present study was conducted at Red Cross War Memorial Children's Hospital (RCWMCH) in Cape Town, South Africa. Methods: Structured literature review: From 1 April …
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Development of A Molecular Gram-Stain Assay For The Diagnosis of Blood Stream Infections Associated With Sepsis
… to cost $24.3 billion annually. Currently, blood culture followed by Gram-stain analysis is the gold standard for diagnosing bacterial infections associated with sepsis. This method generates a high rate of false negative results and, in general, requires 20 to 48 hr to provide results. Both …
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Laboratory findings that occur in Klebsiella pneumoniae blood stream infection in HIV-infected children compared to HIV uninfected children, at a South African children's hospital, Cape Town, 2006–2011: a nested-descriptive cross-sectional study
Background: Bloodstream infection (BSI) caused by Klebsiella pneumoniae (KP), is a leading cause of hospitalassociated childhood mortality. There are limited data on how poor outcomes of KPBSI can be predicted in poorly resourced areas. This study aimed to assess if the profile of differential …
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Development of nanosponges from erythrocyte ghosts for removal of streptolysin-O and α haemolysin from mammalian blood
… such as respiratory, urinary, and intestinal and blood stream infections. If left untreated they can lead to a condition known as sepsis. Sepsis is a whole body inflammatory response that can be fatal. The aim of this study is to develop biomimetic nanosponges from mammalian erythrocyte ghosts, as …
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Zein films as substrates for cell attachment
… from a primary tumor and circulate in the blood stream. Circulating tumor cells play an important role in metastasis. The long term goal of this project is to capture and remocve CTC’s from the blood stream. Numerous studies on glutamine metabolism in cancer indicate that many tumors are …
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Adenovirus-associated pneumonia in South African children : presentation, clinical course and outcome
… Admission to ICU (OR 8.3, 95% CI 2.3-29.0) and blood stream infection (OR 11.2; 95% CI 2.3-54.1) were independent risk factors for mortality. Conclusion: Adenoviral-associated pneumonia is an important cause of pneumonia and CLD in young children in South Africa. Admission to ICU and blood …
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Renal function during profound hypothermia in the dog
… hypothermia in dogs. Hypothermia was induced by blood-stream cooling, via a heat exchanger incorporated in an extra-corporeal pump-oxygenator system (ef Appendix A). Progress was such that by midyear postoperative survival of experimental animals was assured. At this juncture, it was suggested …
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Identification of the role of the sal locus in streptococcus pyogenes virulence during host-pathogen interactions
… appeared to lose the ability to survive in the blood stream, which consequently inhibited systemic dissemination to the spleen. The attenuation of the ΔsalKR mutant in the blood stream was due to its sensitivity to intracellular and extracellular killing by neutrophils. This was most likely a …
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Infection Control: Reducing Hospital Acquired Central Line Bloodstream Infections
… Makic, 2013). It’s estimated that each neonatal bloodstream infection costs about $35,000 and adds about two weeks to a baby’s hospital stay (Akron's Children Hospital, 2015). This project was formulated to reduce the incidence of central line blood stream infections in the neonatal population. …
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Exploring nanoparticles' interactions with blood proteins and visualizing the heterogeneity within hematopoietic cell populations
… onto the particles upon NPs' injection into the blood stream, and form a biological coating named ""protein corona."" Protein corona formation could remarkably affect NPs' blood circulation, their cellular uptake, and targeting efficiency. Because current methods, such as PEGylation, could not …
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Acquired infections in paediatric patients after cardiac surgery
… 2012. The definitions of laboratory confirmed blood stream infections (BSI), urinary tract infections (UTI), and surgical site infections were based on the Centres of Disease Control criteria. Ventilator associated pneumonia (VAP) was diagnosed using a modification of the Clinical Pulmonary …
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Microneedle gastric retention for drug delivery
… loaded with any drug to ensure uptake into the blood stream over the course of several days.
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Identification of Human Adrenal Carcinoma Cells Using Photoacoustic Flow Cytometry
… will be further used in the future to develop a blood assay for early detection of adrenal cancer cells in the blood stream of patients within a clinical setting, aiding in early diagnosis, and consequentially decreased mortality rates in patients.</p>
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Viscous streaming-enhanced inertial particle transport
… to fulfill these wide range of tasks is viscous streaming, a non-linear effect characteristic of the scales above. In this thesis, we first show that numerical simulations based on the Remeshed Vortex Method (RVM) can accurately and efficiently capture viscous streaming dynamics. We test this …
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Polymerní terapeutika pro imunoonkoterapii
… at pH 7.4 (corresponds to the pH of the blood stream), and at a slightly acidic pH 5.5 (corresponds to the microenvironment of the tumor, or endosomes of tumor cells), its rapid hydrolysis occurs. For the second derivative, 5-azidopentanoic acid was used. An uncatalysed click reaction...
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Relationship between Processing Body Formation, Epithelial-to-Mesenchymal Transition, and Invasion in Lung Adenocarcinoma
… their cell-cell contacts, invade, and enter the blood stream which are essential during metastasis. Many transcriptional gene programs are altered during EMT such as activation of mesenchymal transcription factors, like ZEB1, and enhanced response to the TGFβ1 cytokine. In oncogenic contexts, …
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Increasing CLABSI Bundle Compliance in the NICU
… nutrition (TPN). Central line-associated blood stream infections (CLABSIs) have the potential to cause harm in the vulnerable neonate. Current evidence shows that having a CLABSI bundle compliance rate of 95 percent or greater correlates with a reduction in CLABSI occurrences. The purpose …
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