Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"blood oxygenation"”.
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Noninvasive optoacoustic monitoring of blood oxygenation in large blood vessels
Continuous monitoring of cerebral blood oxygenation is critically important for successful treatment of patients with severe traumatic brain injury and patients undergoing cardiac surgery. At present, the techniques for monitoring blood oxygenation are invasive. We propose the noninvasive …
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Development of a microfluidic device for blood oxygenation by photocatalysis
… lungs. A novel microfluidic device for the oxygenation of whole blood has been developed. The device couples a semiconductor, titanium dioxide (TiO₂), thin film that generates oxygen through photocatalysis with a microfluidic network that facilitates diffusion of the dissolved oxygen to red …
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Tissue Blood Flow and Oxygen Consumption Measured With Near -Infrared Frequency -Domain Spectroscopy
… that can continuously, in real-time, measure blood parameters and especially blood oxygenation. This is a very important information in emergency medicine, for persons under intensive care, or undergoing surgery, organ transplant or other interventions.
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Multi and Hyperspectral Imaging of Early Detection of Disease
… The nailfold capillaries are the smallest blood vessels in the body, and deformations in these capillaries are indicators of systemic scleroderma, a rheumatic disease. A hypothesis was formed correlating these deformations with changes in oxygen levels. Two multispectral systems, capable of …
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Correcting the variations of bold signal due to susceptibility-induced magnetic field gradients and its application
… magnetic resonance imaging (fMRI) using blood oxygenation level dependent (BOLD) signals is a tool that is currently used in many cognitive neuroscience studies. However, many studies do not consider susceptibility-induced magnetic field gradients. Susceptibility-induced magnetic field …
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Clinical applications of quantitative photoacoustic imaging
… learning approach were compared to estimate blood oxygenation (sO<sub>2</sub>). A consistent trend of increasing sO<sub>2</sub> with increasing skin pigmentation was observed in all three settings, suggesting that spectral colouring was leading to decreased light penetration at shorter …
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Accurate noninvasive monitoring of fetal tissue oxygenation level
Fetal blood oxygenation level serves as a critical indicator of fetal health throughout pregnancy and labor. However, existing clinical devices predominantly employ invasive techniques, posing risks to both the fetus and the mother. To address this concern, we present a noninvasive method for …
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A multimodal investigation in eye movements
… BNCs. Functional activity is assessed using the blood oxygenation level dependent (BOLD) percent signal change. Task-modulated coactivation is assessed using an ROI-based task modulated coactivation analysis that reveals significant correlation between ROIs.
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Examination of susceptibility effects on functional and dynamic magnetic resonance imaging
… drives certain contrast mechanisms including blood oxygenation level dependent fMRI. The two projects in this work look at the effects of inhomogeneity on functional and dynamic MRI. We simultaneously acquired functional and dynamic MRI (Simulscan) of natural un-cued swallows. Work was done to …
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Fabrication of microfluidic devices for artificial respiration
… machines deliver oxygen gas directly to the blood via external macroscale devices, our technique utilizes a biomimetic photocatalytic process to generate energy from light and thus produce dissolved oxygen from water which is already present in the blood. Blood oxygenation will be achieved by …
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Advances in functional magnetic resonance imaging to facilitate brain research
… magnetic resonance imaging (fMRI) based on blood oxygenation level dependent contrast (BOLD) is one such tool capable of non-invasively mapping functional columns and/or layer responses at working or resting state. However, several challenges exist even for mapping at the ultrahigh field. …
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Expanding the role of functional mri in rehabilitation research
… magnetic resonance imaging (fMRI) based on blood oxygenation level dependent (BOLD) contrast has become a universal methodology in functional neuroimaging. However, the BOLD signal consists of a mix of physiological parameters and has relatively poor reproducibility. As fMRI becomes a …
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A functional MRI study of the distributed neural circuitry of learning and reward
… magnetic resonance imaging (fMRI) with blood oxygenation level dependent (BOLD) contrast was then used to evaluate the brain activation in response to behaviorally characterized electrical stimuli. High resolution anatomical images revealed that subjects with electrode tips positioned …
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Subject and group level changes and comparison in functional connectivity under low vs. high cognitively demanding naturalistic viewing conditions using fmri
… and implements statistical methods applied on Blood Oxygenation Level Dependent (BOLD) signals. The conventional task based designs are very specific and may not reflect day to day activities. The two task conditions in this study are watching a movie called INSCAPE with low cognitive load and …
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Cortical Mechanisms of Human Pelvic Floor Muscle Synergies
… resonance imaging (fMRI) was used to measure blood oxygenation density levels (BOLD) in the brain while subjects performed various prime mover tasks. Our second original experiment involved another set of 10 healthy male subjects who were trained to perform a complex synergy …
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Measurement of retinal vascular permeability in a rat model using spectroscopic optical coherence tomography
… such as Doppler OCT for quantifying blood flow and generating angiography using OCT phase information, polarization sensitive OCT for measuring intrinsic mechanical / optical tissue property using light of different polarizations, and spectroscopic OCT for measuring blood oxygenation …
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From practice to theory: computational studies on fluorescence detection and laser therapy in dermatology
… The changes in the skin concern blood volume, blood oxygenation and scattering in the epidermis. The calculations show that there are some notable differences in the effect changes in the composition of psoriatic tissue has on the efficacy of laser and IPL therapy. Still, …
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Measurement of Cerebral Metabolism and Vascular Function with Magnetic Resonance Imaging
… employs phase-contrast MRI for quantitative blood flow measurement and T2-relaxation-under-spin-tagging (TRUST) MRI for venous oxygenation estimation. During this thesis, I conducted several technical development studies. I first optimized TRUST and phase-contrast MR imaging parameters and …
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The BOLD MRI response of the brain to alterations in arterial blood pressure
The impact of blood pressure changes on cerebral blood flow is an important area of investigation. The cerebral autoregulation mechanism acts to maintain blood supply to the brain, despite changes in blood pressure. Blood flow alterations are closely linked to neuronal activation, and this activity …
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Novel Functional Magnetic Resonance Imaging Analysis Approaches for Investigations of the Dynamics of Resting-State Functional Connectivity
Spontaneous fluctuations of blood-oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI) signals are highly synchronous between brain regions that serve similar functions. This provides a means to investigate functional networks of the human brain; however, most data analysis …
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