Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"blood diseases"”.
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Ailments of the Soul: Blood Transfusions and the Treatment of Melancholy in Seventeenth-Century England
The first animal-to-human blood transfusions performed in seventeenth-century England focused on patients suffering from mental diseases such as melancholy. Many physicians diagnosed melancholy as a disease of the body, mind, and soul in which blood played a key role. Philosophy, religion, and …
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The Role of Cleavage and Polyadenylation Spcific Factor 6 (CPSF6) in Hematopoiesis
… acute myeloid leukemia (AML) and other types of blood diseases associated with abnormal hematopoiesis. CPSF6 is a subunit of the Cleavage Factor I mammalian (CFIm) complex, which regulates post-transcriptional alternative polyadenylation (APA) of pre-mRNAs. Previous research indicated that …
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Multi-scale computational modeling of particle adhesion dynamics under shear flow
… flow conditions. The model is useful in studying blood diseases like thrombotic microangiopathies (TMAs). By modeling interactions between VWF and platelets under physiological shear conditions, a stable web-like scaffold was formed, resulting in a complex network of cross-linked VWF and platelets …
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Custom-Designed Biohybrid Micromotor for Potential Disease Treatment
… and their potential applications on targeted diseases treatment. By means of 2D and 3D lithography methods, microstructures with complex configurations can be fabricated for specific demands. Bovine and human sperm are both for the first time explored as drug carriers thanks to their high …
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Design of a numerical model for simulation of blood microcirculation and study of sickle cell disease
… disease is nowadays one of the most challenging blood diseases, where patients suffer from both chronic and acute episodes of painful medical conditions. In particular, unpredictable crises due to blood vessel occlusion remain one of the least understood stages of the disease, which focuses the …
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Mobilisation, Isolation and Coculture of Haematopoietic Stem Cells
… stem cells (HSCs) mobilized into the peripheral blood (PB) have been used as a preferred source of transplantable stem cells1-3. And umbilical cord blood (UCB) has been introduced as a more attractive HSC source for HSCT, because fetal stem cells in UCB are speculated to be more primitive in …