Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"blimp"”.
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Blimp-1 Regulates Terminal Differentiation of T Cells
The transcriptional repressor-Blimp-1 terminates differentiation of B lymphocytes as well as myeloid cells. Our data show that Blimp-1 is highly expressed in freshly isolated murine primary T lymphocytes, particularly its minor splice variant. Ectopic expression of Blimp-1 by retroviral …
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Einfluß von Blimp-1 auf die Interferonproduktion und Virusvermehrung
… sich mit der Frage, ob der Transkriptionsfaktor Blimp-1 ebenso wie sein humanes Äquivalent PRDI-BF1 die Interferonproduktion reprimiert und somit die Virusvermehrung in Zellen erleichtert. An Blimp-1 exprimierenden L929-Zellen wurde die Interferonproduktion mit Hilfe des RNase Protection Assay …
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Regulation der terminalen B-Zell-Differenzierung durch Blimp-1
… des Keimzentrums. Der Transkriptionsfaktor Blimp-1 ("B lymphocyte induced maturation protein 1") wird als ein „Mastergen“ der terminalen B-Zell-Differenzierung betrachtet und ist in der Lage, die komplexen Differenzierungsprozesse zu Ig-sezernierenden Plasmazellen auszulösen und …
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Feedback Controller Design For Low-Power Autonomous Blimp Robot
… planning algorithms, a low-power autonomous blimp robot that uses buoyancy to reduce power requirements for three-dimensional movement was designed. The blimp has two forward-facing rotors and two vertically-facing rotors. Due to the underactuated nature of the robot, the blimp cannot be …
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Regulation of B lymphocyte terminal differentiation and death by the transcription factor Blimp-1
B lymphocyte induced maturation protein-1 (Blimp-1) und X-box-binding protein-1” (XBP-1) sind als Transkriptionsfaktoren unverzichtbar für die terminale Differenzierung von B-Lymphozyten zu Immunglobulin (Ig)-sezernierenden Plasmazellen. Ebenso stellen die unfolded protein response (UPR) und das …
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A Language and Logic for Programming and Reasoning with Partial Observability
… the prototype belief programming language BLIMP, and used BLIMP to implement several example programs – including an engine controller for the MPL. I will also present Epistemic Hoare Logic (EHL), a program logic for belief programs that enables developers to reason about properties of the …
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REGULATION OF ADAPTIVE IMMUNE RESPONSES TO PLASMODIUM CHABAUDI MALARIA INFECTION
… Whereas the transcription factors Bcl6, Blimp-1, and STAT3 regulate the development of Tfh cells, T-bet and STAT4 direct the commitment of Th1 cells. Since our understanding of the regulation of adaptive protective responses against malaria is poor, the present dissertation aimed to study …
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Investigating the Effect of Antibody-Mediated Feedback on Ongoing Germinal Center Responses
… In addition, we have genetically engineered a Blimp-1-DTR mouse that allows for temporally controlled ablation of plasma cells and, therefore, depletion of antibody titers. Combining these two models has revealed that high levels of antibody produced during B cell responses can modulate …
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Targeting T Cells for the Immune-Modulation of Human Diseases
… functional repressor of the transcription factor Blimp-1, which promotes CTL cytotoxicity and effector cell differentiation. In a cohort of advanced lung cancer patients, miR-23a was upregulated in tumor-infiltrating CD8+ T cells, and its expression correlated with impaired antitumor potential of …
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Passive Acoustic Localization and Tracking with Mobile Robots
… in experiment by controlling the altitude of a blimp-like vehicle using only the self-generated noise and two microphones placed on the bottom of the vehicle. </p>
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PKB/Akt : a critical regulator of lymphocyte, development and function
… of in vitro expanded B cells revealed increased Blimp-1 and Notch3 expression in myr PKB tg B cells, which might be primary candidates involved in their enhanced effector function. In summary, this study clearly shows an important cross-talk between PKB and various critical signalling molecules …
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Giving ground : a personal account of voice, movement and femininity in Texas
My work springs from the place where my body touches Texas. In my thesis report I attempt to lay out my embodied experience of living here and how this intersects with phenomenology and Butler’s theory of the displaced feminine, whilst describing some of the work I have made in response to these …
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The Porcelain Groups
My background in clay has emphasized the development of technical considerations in functional ceramics as well as the search for personal images. The past two years have seen an emphasis on the exploration of technical areas chosen to lead to the development of a familiarity with techniques and a …
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DeTROYt
An attempt to save the city of Detroit, Michigan, and its existing buildings by giving it a new meaning and future. Cars and roads are eliminated. Tiger Stadium is converted into a city-wide freight receiving and shipping facility. A system of pneumatic tubes is implemented in each neighborhood, …