Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 83 for “"blasts"”.
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CELLULAR AND MOLECULAR MECHANISMS OF CHEMORESISTANCE IN ACUTE MYELOID LEUKEMIA
… been implicated, recent studies suggest that AML blasts that survive chemotherapy, known as Chemotherapy Persistent Blasts, enter a senescence-like and diapause state. Though they can contribute to disease recurrence, these Persistent Blasts are not inherently therapy-resistant as they revert to a …
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Computational modeling of blast-induced traumatic brain injury
… little is known about the mechanical effects of blasts on the human head; no injury thresholds have been established for blast effects on the head, and even direct transmission of the shock wave to the intracranial cavity is disputed. Still less is known about how personal protective equipment …
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Numerical Comparison of Muzzle Blast Loaded Structure
… benefit by accurately predicting the response to blasts with little need for test or event data. This thesis reviews fundamental concepts of blast waves and explosives and discusses research in blast scaling. Blast scaling is a method that reduces the computational costs associated with modeling …
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Rodent testing device surrogate for shockwave blast testing
… different techniques for creating the shockwave blasts as well as positioning the rats. There is no device to determine whether or not the rodent animal models actually experiences a true blast wave in a given set up. This device was developed as a method for verifying rodents undergoing true …
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Changes in material characteristics of AISI 430 stainless steel plates subjected to repeated blast loading
… plates were subjected to repeated explosive blasts, using a plastic explosive (PE4). The charge mass was varied for each test and the stand-off distance was kept constant at 150 mm for uniform loads and 13 mm for localised loads. Two plates were selected to investigate the uniform loading …
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Development of a software tool to investigate the local & global response of buildings to blast loading
… of building structures subjected to external blasts. A software tool to assess the response of structure to blast loads is firstly presented. The proposed tool integrates a staged process and can broadly be broken down into three core modules: the blast load condition, the response of the …
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Alcohol-Cues Relate to Self-Perceptions of Aggression
… measure of length and loudness of noise-blasts), evaluated experimenter performance (relational aggression measure of ratings and recommendation of experimenter), and completed surveys on frequency of alcohol consumption, alcohol expectancies, and acceptance of aggressive behaviors. …
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Simulation of the generation and propagation of blast induced shock waves
… developed and used to monitor a series of test blasts carried out in limestone and chalk. The repeatability of single hole test shots is investigated. It is shown that in the near field single holes are generally highly repeatable even with relatively major differences in design. It is also …
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Saharan Fallout: French Explosions In Algeria And The Politics Of Nuclear Risk During African Decolonization (1960–66)
… unprecedented era of decolonization. The French blasts coincided with the Algerian War (1954–62), continued after Algerian Independence, and intersected with decolonization struggles in neighboring African territories. At the same time, Saharan fallout illuminated processes of Cold War …
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ΕΠΙΔΡΑΣΗ ΤΟΥ ΦΟΡΒΟΛΙΚΟΥ ΕΣΤΕΡΑ ΤΡΑ ΣΕ ΑΝΘΡΩΠΙΝΑ ΛΕΥΧΑΙΜΙΚΑ ΛΕΜΦΟΚΥΤΤΑΡΑ
… WHICH SHOWS TWO PHENOTYPES, THAT OF LARGE THYMIC BLASTS (ABOUT 50% OFTHE CELLS). 2) THE SDK CELL LINE, WHICH INCLUDES CELLS WITH EITHER THE PHENOTYPE OF MATURE B LYMPHOCYTES (60-70% OF THE CELL POPULATION) OR OF PLASMACYTOID OR PLASMA CELLS (THE REMAINING CELLS. IT HAS BEEN FOUND THAT TPA, AT THE …
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The effects of different degrees of confinement on the deformation of square plates subjected to blast loading
… the effcts of the degree of confiement for air blasts only. The response of a structure subjected to a blast load is dependent on several factors; for instance stand off distance, geometry and mass of explosive, geometry of the structure, medium (air, water, soil) and degree of confinement. …
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Stimulation of donor t-cells with leukemic blast-loaded dendritic cells for the generation of leukemia-specific immunity in the context of allogeneic stem cell transplantation
… (dDCs) loaded with irradiated patient leukemic blasts (p-LBs). The immune reactivity of the stimulated donor-TCs (dSTCs) to the pLBs and other haematopoietic derived patient cells, and a third party leukemic blast (3PLB) were measured by ELISPOT for IFN-g secreting cells and compared with the …
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Field Behavior Comparison of 8 Species of California Desert Ants
… running time between stops, and response to air blasts (Messor oergandei and Pheidole barbata were the least aggressive). Solenopsis maniosa was one of the three worst glass climbers, along with Pogonomyrmex californicus and Pogonomyrmex magnacanthus; Conomyrma bicolor and Myrmecocystus species …
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Regulation of Myeloid Leukemia Cells by Platelet Factor 4
… and able to repopulate eradicated leukemic blasts, making LSCs an important target in AML. However, their interactions with and regulation by the bone marrow microenvironment deserve further exploration. Here, we examined the efficacy of the megakaryocyte-derived chemokine platelet factor 4 …
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Blasting Design Using Fracture Toughness and Image Analysis of the Bench Face and Muckpile
… Splitting test. Blasting data from twelve (12) blasts at four (4) different quarries were analyzed. Based on this data set, an empirical relationship, ESE=11.7 RR801.202 KIC4.14 has been developed. Using this relationship, based on the predicted blasting energy input for a desired eighty-percent …
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THE METHIONINE CYCLE AS A NOVEL THERAPEUTIC TARGET IN NPM1C DRIVEN ACUTE MYELOID LEUKEMIA
… expression of NPM1c in Murine Embryonic Fibroblasts (MEFs) leads to an unbalanced methionine-cycle with decreased ratio between S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH), key metabolites of the methionine cycle. Decreased SAM/SAH ratio is known to inhibit cellular …
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An investigation of the biomechanical response from shock wave loading to the head
… exposed to a first series of fifteen simulated blasts, changing pressure magnitudes and orientation of the sample. Subsequently, apertures were introduced in the spheres and a second series of fifteen simulated blasts was conducted, reproducing the same shock wave overpressure magnitudes and …
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Verfahren zur Herstellung gefriergetrockneter Kollagenschwämme mit definierter Porenstruktur
… collagen suspension. The behaviour of human fibroblasts within the collagen sponges were investigated in vitro. The ex-pected influence of pore structure and size on cell behaviour could not be confirmed in case of fibro-blasts. However, fibroblast migration and proliferation could be proved over …
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Modelling the affinity maturation of B lymphocytes in the germinal centre
… to be selected and become high affinity plasma blasts and memory B cells. This conclusion has been partially confirmed by recent experimental results (Toellner, unpublished).
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