Global ETD Search
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Showing 1 to 3 of 3 for “"bixin"”.
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The module mir156/spl affects bixin biosynthesis pathway in annatto (Bixa orellana L.)
… Annatto produces a main apocaterotenoid namely bixin, a unique natural dye. This compound is highly used in the textile, pharmaceutical and food industries, among others, making annatto an important crop in both ecological and economic aspects. Despite its relevance, there are several gaps for …
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Characterization of the Molecular Mechanisms of Xenobiotic-Induced NRF2 Activation for Disease Prevention and Intervention
… dissertation, the achiote-derived apocarotenoid bixin was characterized as a novel NRF2 activator. Bixin pre-treatment prevented solar UV-induced photodamage and hair graying in several mouse models. These results suggest that using bixin to activate NRF2 is a feasible strategy to prevent …
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The Temporal and Contextual Relationship of NRF2 Activation and Cancer
… of NRF2, pharmacological induction of NRF2 using bixin increased cellular glutathione levels which in turn combatted oxidative stress and mitigated radiation-induced dermatitis in non-cancerous skin keratinocytes. Meanwhile, in relation to the dark side of NRF2, in BRAF V600E mutant melanoma, …