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Showing 1 to 6 of 6 for “"bisulphite sequencing"”.

  1. DNA methylation: the "stable" epigenetic mark

    … the analysis genome-wide, I use a target capture bisulphite sequencing method to evaluate methylation fidelity in the subclonal cell lines more globally. I find that CpGs exhibiting intermediate methylation at the cell population level, are generally unfaithfully inherited between cell divisions …

    cambridge Repository record for DNA methylation: the "stable" epigenetic mark (opens in a new tab)

  2. Functional analysis of 5-hydroxymethylcytosine

    … the techniques used for 5-mC detection, such as bisulphite sequencing and methyl-sensitive restriction digestion, are incapable of distinguishing between 5mC and 5hmC implying the necessity not only to develop techniques specific for 5-hmC characterization but also reevaluation of previously …

    edinburgh Repository record for Functional analysis of 5-hydroxymethylcytosine (opens in a new tab)

  3. DNA Methylation Landscape of the Fibrinogen Gene Cluster in the Equine Embryo

    The initial weeks of equine pregnancy includes the unique phase of embryo mobility from day 9 until fixation on day 15. Fixation of the embryo to the uterine wall occurs before a microvillous attachment at ~day 40. Throughout the mobility period the equine embryo expresses and secretes fibrinogen, …

    calgary Repository record for DNA Methylation Landscape of the Fibrinogen Gene Cluster in the Equine Embryo (opens in a new tab)

  4. Understanding immune priming in Pacific oysters: A multi-omics exploration of transcriptomic, epigenetic and microbiome regulation

    … approach involving RNA-Seq, 16S amplicon sequencing and whole genome bisulphite sequencing was utilised to interrogate whether immune priming resulted in long-lasting molecular alterations to the oyster transcriptome, microbiome and epigenome (Chapters 3-5). For naïve oysters, …

    exeter

  5. Understanding immune priming in Pacific oysters: A multi-omics exploration of transcriptomic, epigenetic and microbiome regulation

    … approach involving RNA-Seq, 16S amplicon sequencing and whole genome bisulphite sequencing was utilised to interrogate whether immune priming resulted in long-lasting molecular alterations to the oyster transcriptome, microbiome and epigenome (Chapters 3-5). For naïve oysters, …

    exeter