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Showing 1 to 5 of 5 for “"biphasic kinetics"”.
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Cadherin recognition and specificity
… results revealed that cadherin binding exhibits biphasic kinetics. Further studies with domain deletion mutants showed that the EC1 domain of cadherin extracellular region is responsible for the first phase of the biphasic kinetic profile. The affinity and dissociation rate of EC1 bond were then …
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The glutathione S-transferases : kinetics, binding and inhibition
… most detailed investigations of the steady-state kinetics of glutathione S-transferase have been performed with isoenzyme 3-3 (class Mu) and the substrate 1,2-dichloro-4-nitrobenzene (DCNB). Explanations for the apparently anomalous non-hyperbolic kinetics have included subunit cooperativity, …
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Dynamics and mechanism of spin-state interconversion in transition metal complexes. (Volumes I and II)
The kinetics of the $\Delta$S = 2 spin-state interconversion in d$\sp6$ transition metal complexes are examined. A series of compounds having a polypyridyl-based ligand framework are described which allow for systematic modification of molecular geometry. A nanosecond time-resolved laser …
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Gating Mechanisms of The Canonical Trp Channel Isoform Trpc4
… receptor, µ agonist DAMGO elicited currents in a biphasic manner, with an initial slow phase preceding a second, rapidly developing phase. While the currents were dependent on intracellular Ca<sup>2+</sup> and phosphatidylinositol 4,5-bisphosphate (PIP<sub>2</sub>), both Ca<sup>2+</sup> and …
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The Membrane Polypeptides of the Vacuolar System: Composition and Recycling
… radioactivity was lost from cells with biphasic kinetics. 20-50% of the cell-associated radiolabel was rapidly digested (t<sub>1/2</sub> ≅ 1 h) and recovered in the culture medium as monoiodotyrosine. 50-80% of the label was lost slowly from cells (t<sub>1/2</sub> ≅ 24-30 h). …