Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"biotin labelling"”.
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Characterisation of oncogenic pathways driving the pathogenesis of prostate cancer
… a BioID system, which employs promiscuous biotin labelling and subsequent mass spectrometry, and confirmed via co-immunoprecipitation in various models of PCa. Knockdown of LGMN and HSD17B4 is selectively cytotoxic to PCa cells, indicating that targeting of these two enzymes may provide …
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Protein interaction studies on the titin A150 domain using proximity-dependent biotinylation
… behind HMERF. In this study, proximity dependent biotinylation (PDB) was used to screen for protein interactions. PDB was conducted using the biotin-ligase UltraID fused to a titin fragment. This study encompasses the creation of the titin-UltraID fusion genes, the functional validation of the …