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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 234 for “"biosynthetic pathway"”.
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Investigation of class v lanthipeptide biosynthetic pathway
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites
… This thesis describes the synthesis of ESH pathway enzyme substrates, with the main focus on the synthesis of the EgtE enzyme substrate, ESH biosynthetic precursor, R- and S-(β-amino-β-carboxyethyl) ergothioneine sulfoxide. In order to prove that synthesized compounds are indeed …
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Regulation of The Candida Albicans Arginine Biosynthetic Pathway
… the activation of alternative carbon metabolism pathways suggesting that the pathogen is exposed to a glucose poor environment. Changes in amino acid metabolism are not observed, with the only exception of arginine biosynthesis. The strong upregulation of the arginine biosynthetic (<em>ARG</em>) …
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Elucidation of the Biosynthetic Pathway for 7-Deazapurines
… of GTP to the previously identified queuosine biosynthetic intermediate 7-cyano-7-deazaguanine (preQ₀) is demonstrated using purified, recombinant enzymes. Also included herein is a kinetic, spectroscopic, and mechanistic characterization of QueE, an enzyme that catalyzes the third step in the …
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Newly Discovered Intermediates in the Chlorophyll a Biosynthetic Pathway
… intermediates in a four-branched chlorophyll a biosynthetic pathway (Rebeiz et al., 1981, In: Photosynthesis Vol. 5, Edited by Akoyunoglou, G., Int. Sci. Services. Balaban, Israel, pp. 197-212).
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Combinatorial biosynthetic pathway engineering for microbial production of biofuels
… of biofuels comes from the optimization of the biosynthetic pathway. We investigated and developed new combinatorial strategies for the optimization of the cellobiose utilization pathway, a pathway which is important in biofuel production. One strategy focused on optimizing enzyme combinations …
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Intermediate metabolism of the chlorophyll {\it b\/} biosynthetic pathway
Chlorophylls are compounds of extreme importance in the biosphere. Despite intense studies for the past 100 years, chlorophyll biosynthesis remains a very active field of research.
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Development of antibodies for characterizing the Arabidopsis flavonoid biosynthetic pathway
… enzymes of the Arabidopsis thaliana flavonoid biosynthetic pathway were developed using conventional and phage antibody technology. cDNAs from Arabidopsis coding regions of chalcone synthase (CHS) and chalcone isomerase (CHI) were sub-cloned in frame into a bacterial expression vector as …
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Genetics and expression of the anthocyanin biosynthetic pathway genes in soybean
Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:44:41Z Item is restricted indefinitely.
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Genetic studies of candidate genes in the glycoalkaloid biosynthetic pathway of potato
… of genomic DNA coding for regions of five SGA biosynthetic candidate genes were amplified, cloned and sequenced [3-hydroxy-3-methylglutaryl coenzyme A reductase 1 and 2 (HMG1, HMG2); 2,3-squalene epoxidase (SQE); solanidine galactosyltransferase (SGT1); and solanidine glucosyltransferase …
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Functional Evolution and Origin of Enzymes of the Bacterial Glycogen/Starch Biosynthetic Pathway
… how enzymes of the bacterial glycogen/starch biosynthetic pathway originated. Additionally, we want to understand how the function of the control enzyme of this pathway, ADP-glucose pyrophosphorylase (ADP-Glc PPase), has evolved. This is important because starch is a vital part of agriculture …
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Targeting final steps of sugar nucleotide biosynthetic pathway against <i>Aspergillus fumigatus</i>
… elicits antifungal activity. Sugar nucleotide biosynthetic pathway suggests that cell wall carbohydrates are made from three key sugar nucleotides: UDP-GlcNAc, UDP-Glc and GDP-Man. Targeting UDP-GlcNAc may affect chitin and GAG. Targeting UDP-Glc may affect glucan, galactomannan and GAG. …
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Studies of the Chlorophyll Biosynthetic Pathway Between Protoporphyrin Ix and Magnesium-Protoporphyrin Ix Monoester
Made available in DSpace on 2015-05-14T15:10:00Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7821247.PDF: 3642484 bytes, checksum: fb3fd656cbb61635a722e7cf0f540511 (MD5) Previous issue date: 1978
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Identification and preliminary characterization of the 2,5-diphenyloxazole biosynthetic pathway in streptomyces polyantibioticus SPRT
… (DPO). Based on the structure of DPO, a biosynthetic scheme for the synthesis of this molecule was proposed, whereby a non-ribosomal peptide synthetase (NRPS) condenses a molecule of benzoic acid with 3-hydroxyphenylalanine. The dipeptide is converted to a diphenyloxazole derivative by …
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Substrate elucidation and mutasynthesis: Characterisation of the biosynthetic pathway of a tripyrrolic secondary metabolite, prodigiosin
… was only elucidated in the 1960s and the biosynthetic pathway remained mainly unknown until the 2000s. This secondary metabolite results from a bifurcated pathway where monopyrrole 2-methyl-3-pentyl-1H-pyrrole (MAP) and bipyrrole 4-methoxy-1H,1'H-2,2'-bipyrrole (MBC) are produced …
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Total synthesis of cyclotryptamine and diketopiperazine alkaloids and biosynthetic pathway investigation of unsymmetrical diketopiperazine dimers
… of (-)-Naseseazine C and Identification of its Biosynthetic Pathway The biogenesis of unsymmetrical dimeric diketopiperazines is investigated, in collaboration with the Sherman group at the University of Michigan. Sequencing and mining the genome of Streptomyces sp. CB MQ-030, known to produce …
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The tyrosine regulated DAHP synthase and the biosynthetic pathway of aromatic amino acids in Saccharomyces cerevisiae
3-Deoxy-D-arabino-Heptulosonat 7-Phosphat (DAHP) Synthasen (EC 2.5.1.54) katalysieren die erste Reaktion des Biosyntheseweges. Das aus der Glykolyse kommende Phosphoenolpyruvat (PEP) und das aus dem Pentosephosphatweg stammende Erythrose-4-Phosphat (E4P) werden zu DAHP kondensiert. In der …
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Computational investigation of the Plasmodium falciparum fatty acid biosynthetic pathway toward the discovery of novel antimalarials
… used for the identification of novel pathway-based antimalarial compounds.
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A Comparative Study of the Sterol Biosynthetic Pathway in Sterol-Synthesizing and Non-Sterol-Synthesizing Fungi
Made available in DSpace on 2014-12-14T04:37:39Z (GMT). No. of bitstreams: 1 7616214.pdf: 6721025 bytes, checksum: f44198700cbaf5ce82ec9d5790f8ac08 (MD5) Previous issue date: 1976
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