Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 406 for “"bioreactor"”.
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Stress in a Microgravity Bioreactor
… the design and development of a cell stretching bioreactor device that can work in conjunction with a Random Positioning Machine (RPM) apparatus. Microgravity environments, such as in space, have been shown to induce alterations in cellular development due to inadequate mechanical loading of …
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Bioreactor engineering for tissue engineering application
Lo scopo di questo lavoro di tesi è la caratterizzazione metrologica di un bioreattore con l’intento di aumentare la riproducibilità e l’affidabilità dei processi di Ingegneria tessutale (Tissue Engineering, TE). La Tissue engineering (TE) o ingegneria dei tessuti è la disciplina che studia la …
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Enantioseparation using a counter-current bioreactor
… chromatography (CCC) as a small footprint bioreactor/separator for manufacture of enantiopure chiral molecules was explored, using as a model reaction the isolation of L-amino butyric acid (L-ABA) from a DL-ABA racemate and the enantioselectivity of D-amino acid oxidase (DAAO). …
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Performance and Fouling during Bioreactor Harvesting
… flow filtration has many advantages for bioreactor harvesting as the permeate could be introduced directly to the subsequent capture step, the process is easy to scale up, and fouling of the filter is limited by the cross flow. However, membrane fouling has limited its widespread use. …
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Cardiac tissue engineering : bioreactor cultivation parameters
… cells, polymer scaffolds, and tissue culture bioreactors, we could engineer cardiac muscle mimicking native tissue in structure and function in the presence of appropriate biochemical and physical signals. The specific objectives were to: ( 1) vary key parameters of the model tissue …
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pH control in a miniaturized bioreactor
A miniaturized bioreactor with a volume on the order of 100 [micro]l has been built with the aim of increasing the efficiency of the screening process for various microbial cultures. Unlike larger reactors currently in use, the current miniaturized design lacks a method of pH control. Without pH …
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Characterization of a perfused 3D liver bioreactor
… an assaying tool, I used an existing multi-well bioreactor that allows for formation of perfused, three dimensional tissue structures, and began characterization of tissue behavior over time. One issue in the multi-well bioreactor is the unknown profile of cell retention over time, which is an …
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Hydrodynamic Characterization of an Arterial Flow Bioreactor
An in vitro arterial flow bioreactor system for the generation of physiological flows in a biological environment was designed, constructed, and characterized. The design was based on models previously used to investigate the response of endothelial cells to shear. The model interfaces a bioreactor …
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Facultative Bioreactor Landfill: An Environmental and Geotechnical Study
… of Municipal Solid Waste treatment is known as bioreactor landfill technology. Bioreactor landfills are sanitary landfills that use microbiological processes purposefully to transform and stabilize the biodegradable organic waste constituents in a shorter period of time. One of the most popular …
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Production of biopolymer using a membrane-based bioreactor
… the production of PHB in a novel membrane-based bioreactor. Direct gas sparging is MM’s current method of gas delivery, but one of NASA’s potential applications for this system would be in microgravity where gas bubbles will not rise, making mass transport and exchange/resupply of gas almost …
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Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor
… and extreme low concentrations. Membrane bioreactor (MBR) used in this study is novella better water reclamation technology that shows several advantages including stable operation conditions due to long solid retention time (SRT); concentrated mixed liquor suspended solids (MLSS); and low …
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Hydraulic evaluation of a denitrifying bioreactor with baffles
Denitrifying ‘woodchip’ bioreactors are an effective conservation practice to reduce nitrate-nitrogen (NO3-N) loss from tile drained agricultural areas. They enhance the naturally occurring denitrification process via the addition of woodchips and maintenance of anoxic conditions. Bioreactors tend …
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Micro-bioreactor design for Chinese hamster ovary cells
The research objective is to design a micro-bioreactor for the culture of Chinese Hamster Ovary (CHO) cells. There is an increasing demand for upstream development in high-throughput micro-bioreactors specifically for the recombinant CHO cell line, an important cell line for producing recombinant …
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Bioreactor Fill Process Control Using Inline Concentration Measurement
… control strategy for filling an agitated, gassed bioreactor. An optimization methodology for selecting an appropriate post-fill target concentration and for quantifying the economic benefit of reducing variability is proposed.
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Scale-up and Measurement Enhancements of a BioGenerator Bioreactor
… oxygen uptake and distribution within the bioreactor. Study into the search for hyperacidophiles thriving in ultra-low pH conditions revealed an interesting finding from the red algae Cyanidium caldarium that was demonstrated to show observable growth to pH -0.85 (19.5% w/w H2SO4), …
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Submerged-Membrane Bioreactor for the Treatment of NASA Wastewater
… wastewater treatment processes. Membrane bioreactors present a possible means of implementing biological wastewater processing in a microgravity compatible manner.A novel submerged-membrane bioreactor was constructed to examine the treatment efficiency of a NASA wastewater ersatz. The …
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In-situ Ammonia Removal Of Leachate From Bioreactor Landfills
… waste management is to operate the landfill as a bioreactor. Bioreactor landfills are controlled systems in which moisture addition and/or air injection are used as enhancements to create a solid waste environment capable of actively degrading the biodegradable organic fraction of the waste. …
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Bioremediation of Phenolic Compounds in Circulating Packed Bed Bioreactor
… in continuously operated circulating packed bed bioreactors (CPBBs). The biodegradation of individual phenol, o-cresol, and p-cresol and mixtures of these compounds (binary and ternary mixtures) were studied. In addition to creating kinetic data on biodegradation of these contaminants, toxicity …
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