Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1325 for “"biophysics"”.
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Dendritic biophysics and evolution
… issues limit our understanding of dendritic biophysics. In addition to distorted electrophysiological measurements, prior studies have largely been limited to ex vivo preparations from rodent animal models, providing little insight for computation in the awake human brain. In this thesis, we …
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Biophysics of Helices: Devices, Bacteria and Viruses
A prevalent morphology in the microscopic world of artificial microswimmers, bacteria and viruses is that of a helix. The intriguingly different physics at play at the small scale level make it necessary for bacteria to employ swimming strategies different from our everyday experience, such as the …
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Molecular Biophysics of Mammalian and Fungal Macromolecular Assemblies
<p>Nuclear Magnetic Resonance Spectroscopy (NMR) is a powerful and highly versatile analytical tool that allows for the collection of data reflecting the macromolecular organization of an ordered structure, and even intramolecular interactions of nuclei. This thesis details two projects that …
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The structure, biophysics and bioengineering of secretory immunoglobin A
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-12-01
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Examining the biophysics of ultrasound and contrast agent induced angiogenesis
… This thesis seeks to explore the biophysics of ultrasound-ultrasound contrast agent-induced capillary angiogenesis, specifically examining the role of the ultrasound contrast agent in creating bioeffects that lead to subsequent angiogenesis. The mechanistic exploration examines …
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Taming Quantum Noise in the Open: Spin Biophysics under Optimal Control
The quantum control of spin-correlated radical pairs (SCRPs) holds promise for the targeted manipulation of magnetic field effects (MFEs), with potential applications ranging from the design of noise-resilient quantum information processors to genetically encodable quantum sensors. However, …
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Dosimetric characterization of a miniature x-ray source for biophysics studies
Tritium is a low energy beta emitter that is found in abundance at CANDU nuclear power plants and is a cause of concern since it accounts for roughly thirty three percent of the total occupational exposure of nuclear workers. According to current standards, the radiation weighting factor for all …
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Molecular dynamics simulations and neural network solutions for applications in biophysics
… computational techniques. In particular, biophysics is a field of science that has continually benefited from the advancement of computers. In biophysics, numerical models of biological phenomena generated from techniques traditionally used in mathematics and physics are solved using …
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Insights into the ecophysiology and biophysics of microbes involved in fermentation
Bramley apple microflora was shown to consist of Aspergillus, Cladosporium, Fusarium, Penicillium and other fungi. Some of these fungi were used for studies to determine biophysical activities of key cellular stressors present during cider fermentations: sugars, ethanol, and glycerol. Generally, …
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Teaching and learning cellular biophysics : propagated action potential simulation in Matlab
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000.
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RNA-MEDIATED PHASE SEPARATION OF 53BP1: CONNECTING CONDENSATE BIOPHYSICS TO DNA DAMAGE RESPONSE
Biomolecular condensates, also known as membraneless organelles, are intracellular compartments which can form via liquid-liquid phase separation (LLPS) where biochemical reactions concentrate within the cell. An example of such condensates are DNA damage response (DDR) foci, proteins and RNA …
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Flow manipulation in soft systems: biophysics and microfluidic discovery through scalable software design
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
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The impact of bacteria on the biophysics of water retention and flow in soil
… has investigated the impact of bacteria on the biophysics of water retention and flow, aiming to elucidate the effect of three key components produced by the model organism, Pseudomonas fluorescens SBW25. Cellulose is an extracellular polysaccharide involved in the formation of the matrix of the …
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Protein Biophysics in Hollow-Core Photonic Crystal Fibres: Label-Free Monitoring of Biomolecules in Optofluidic Waveguides
Proteins are the central building blocks of life, and experimental methods for their study are fundamental to deepening our under- standing of biology and the life sciences. When studying protein interactions, we seek new experimental methods that can detect and monitor proteins in solution, at …
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Statistical Kinetics and Nonequilibrium Thermodynamics of Driven Systems: Stochastic Methods and Applications to Single-Molecule Biophysics
Advances in condensed-phase spectroscopy have permitted the ability to obtain time traces of biomolecules at the single-molecule level of detail. These real-time trajectories provide details that are typically unavailable in ensemble-averaged experiments, such as the effect of conformational …
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Understanding the membrane biophysics of alpha-Synuclein and its role in membrane curvature induction and structural remodeling
Alpha-Synuclein (aSyn) is a 140 amino acid, intrinsically disordered protein that adopts an extended amphipathic alpha-helical structure upon binding the membrane. aSyn is the major proteinaceous component of insoluble fibrillar Lewy bodies, a hallmark of Parkinson's disease (PD). The precise roles …
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New Tools for Structural Biology and Biophysics: High-Throughput Fluorine Solid-State NMR and Applications to Membrane Proteins
Solid-State Nuclear Magnetic Resonance (SSNMR) spectroscopy is a powerful method for characterizing the structure and dynamics of crystalline and amorphous solid compounds, materials, and biological systems. When applied to biomolecular systems such as membrane proteins, it can provide access to …
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