Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"bioorganometallic"”.
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Design, synthesis and biological evaluation of bioorganometallic metallarectangles
Malaria is a devastating mosquito-borne disease, characterized by high levels of morbidity and mortality. The absence of a suitable vaccine to offer protection and the emergence of drug-resistant parasite strains continues to be the driving force behind the development of new antimalarial agents. …
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Development of new bioorganometallic metallodendrimers as in vitro anticancer agents
… agents. Hence, the design and study of bioorganometallic complexes as potential therapeutic agents may eventually lead to the identification of new drug candidates. The purpose of this study was to synthesize and characterize a series of polynuclear transition-metal-containing complexes …
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Development of organosilane-containing bioorganometallic compounds evaluated as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis
… and pharmacological evaluation of new bioorganometallic organosilane-containing compounds based on thiosemicarbazone (TSC),quinoline and benzothiazole scaffolds. Selected thiosemicarbazone-containing ruthenium(II), rhodium(III) and palladium(II) metal complexes were also studied. The …
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Toward Hydrogenase mimicry : subjecting the problem to three different approaches
… approaches. The first strategy used here is bioorganometallic. A wide range of sulfur containing ferrocene-peptide derivatives were synthesized and fully characterized. As a second approach, organic self-assembled oligoquinoline were designed and synthesized. These two kind of structures were …
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The synthesis characterization and application of novel N-ferrocenoyl peptide derivatives
… out as the last step in the preparation of such bioorganometallic compounds as the ferrocene moiety can prove sensitive to the conditions employed during peptide synthesis.
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Mechanisms of action and inhibition of [4Fe-4S] proteins IspG and IspH in isoprenoid biosynthesis
… and catalyze 2e-/2H+ reductions. In this study, bioorganometallic mechanisms are proposed for IspG and IspH catalyses, where direct iron-carbon interactions play important roles. This is a new type of catalytic mechanism of iron-sulfur enzymes, and is supported by extensive characterizations of …
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Solid Phase Synthesis and Biological studies on metal conjugates of bioactive peptides for targeted delivery
… delivery. This represents a novel application of bioorganometallic chemistry in biological systems.
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EMISSIVE PEPTIDE NUCLEIC ACIDS (PNAS): POTENTIAL TOOLS FOR INNOVATIVE DIAGNOSTICS AND THERAPEUTICS
… field. III. Development of a luminescent bioorganometallic Ir-PNA conjugate as potential dual-action system against cancer Organometallic cyclometalated iridium (III) complexes, containing two phenylpyridine ligands and a phenathroline as third ligand, display excellent photophysical …