Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"biomimetic synthesis"”.
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Biomimetic synthesis of meroterpenoid natural products using dearomatization strategies
… biologically active compounds. The first total synthesis of the PPAP natural product garcibracteatone was achieved in four linear steps from phloroglucinol (0.6% overall yield). The key biomimetic synthetic step was an oxidative radical cyclization cascade reaction, where four new carbon-carbon …
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Biomimetic synthesis of natural products via reactions of ortho-quinone methides
In recent times, natural product synthesis has become central to many scientific fields; from chemistry, through to biology and pharmacology. As synthetic chemists, natural products are attractive targets due to their interesting and complex structures, combined with some intriguing biological …
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NATURAL POLYPHENOLS AS LEAD COMPOUNDS IN THE SYNTHESIS OF ANTITUMOR AGENTS AND OTHER USEFUL PRODUCTS
NATURAL POLYPHENOLS AS LEAD COMPOUNDS IN THE SYNTHESIS OF ANTITUMOR AGENTS AND OTHER USEFUL PRODUCTS Abstract Some polyphenol dimers, such as lignans, neolignans and stilbenoid lignans, because of their biological properties as well as their structural variety, are an attractive target for chemical …
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Bioenabled Synthesis of Anisotropic Gold and Silver Nanoparticles
… Since the underlying growth mechanism for the biomimetic synthesis of APMNs remains elusive and controversial, the other objective is to elucidate the molecular interactions between inorganic species and biopolymers during the course of NP evolution. Fluorescent quenching and 2D NMR experiments …
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Synthesis of the Antimalarial Flindersial Alkaloids
… has been successfully demonstrated in the synthesis of all the anti-malarial Flindersia alkaloids. Previous work on the biosynthesis of the related natural products borreverine and isoborreverine inspired us to synthesize racemic flinderoles A, B, and C in as few as three synthetic steps …
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Total synthesis of oxaphenalenone natural products
… lactone E. Our initial efforts achieved the synthesis of corymbiferan lactone E through the use of crossed-Claisen condensation of an isochromanone substrate followed by an interesting Au(I)-mediated 6-endo-dig hydroarylation. Subsequent studies implemented closely-related synthetic …
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SYNTHESIS OF NATURAL-DERIVED POLYPHENOLS AS POTENTIAL ANTICANCER AGENTS
… and natural products research focuses on the biosynthesis and the study of chemical properties and biological functions of secondary metabolites. These are organic compounds not ubiquitous in all organisms, and represent an expression of the individuality of the species; secondary metabolites do …