Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 114 for “"biomedical imaging"”.
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Computational Methods for Biomedical Imaging
… and advance the state of the art in methods for biomedical imaging and disease diagnosis. We demonstrate the generation of non-diffracting beams using Lee Holography, and argue that the rich depth information made possible by these beams is well-suited for machine learning applications, where 2D …
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Enabling Biomedical Imaging Diagnostics using Optical Methods
… thesis work applies optical schemes to existing biomedical imaging techniques to improve the performance of present state-of-the-art biomedical imagers, and is in two parts. In the first part, a fast and simple optical time-gate scheme for counting single photons is presented. The gate is useful …
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Development and characterization of fiber-based systems for biomedical imaging
… thesis focuses on the instrumentation aspect of biomedical imaging with the use of optical fiber probes across three different disciplines. This includes the design and development of novel fiber optic based techniques and instruments in fields of optical coherence tomography (OCT), …
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Fluorinated Nanoparticles: A Novel Technology Platform for Multimodal Biomedical Imaging Applications
… in microbubble contrast agents for ultrasound imaging, positron sources for PET imaging, and as an imaging probe in 19F MRI. Additionally, fluorinated organic compounds generate a high ionization yield of fluorine in secondary ion mass spectrometry (SIMS), which is gaining recognition as an in …
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Novel time resolved optical and machine learning methods for label free biomedical imaging
… is to develop novel nonlinear optical imaging techniques and algorithms for studying mitochondrial heteroplasmy, one of the markers of mitochondrial disorder where the cells or tissues contain a mixture of healthy and diseased mitochondria. The defects in Electron Transport Chain (ETC) …
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Integration of Biomedical Imaging and Translational Approaches For Management of Head and Neck Cancer
… whether the currently available clinical imaging tools can be integrated with radiotherapy (RT) platforms for monitoring and adaptation of radiation dose, prediction of tumor response and disease outcomes, and characterization of patterns of failure and normal tissue toxicity in head and …
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Opto-Electronic Modulation of Quantum Dots by Cells and Bioactive Molecules
… myriad applications in photovoltaic cells, biomedical imaging, targeted drug delivery, and quantum information processing. These have led to much research on their interactions with other systems. For biological systems, research has focused on the biocompatibility and cytoxicity of QDs in …
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Adaptive Fiber Source for Label-free Nonlinear Microscopy
… in many areas, such as high-power fiber lasers, biomedical imaging, and chemical sensing, as well as a platform for investigation of intriguing physics phenomena. In this thesis, we present a simple yet effective way of controlling nonlinear effects at high peak power levels in MMFs. This is …
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Imaging through scattering
… about hidden scenes, in particular for biomedical applications. Imaging through scattering media has long been a challenge, as scattering corrupts scenes in a non-invertible way. The use of near-visible optical spectrum for biomedical purposes has many advantages, such as optical …
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Multi-Material Discrimination Using Photon Counting Spectral Computed Tomography
… (CT) has applications in many areas including biomedical imaging, defense and security, geophysical imaging of rock composition and in materials and chemical imaging. Dual or multi-kVp x-ray exposure when using an energy-integrating detector has been proposed and demonstrated in the past for …
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Optical Scanning Holography for 3-D Imaging of Fluorescent Objects in Turbid Media
… heterodyne 2-D scanning technique for 3-D imaging of fluorescent objects in turbid media is described and experimentally demonstrated. For the first time, 3-D imaging of fluorescentobjects in turbid media by a holographic method is achieved, and the diffused photon rejecting process through …
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Ptychography for Nonlinear Optical Microscopy
… fluorescent microscopy for label free optical biomedical imaging. In order to demonstrate this method I describe a method for the generation of a numerical sample of collagen fibrils, produce a set of numerical diffraction measurements. I introduce a novel Ptychography model for the …
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Optical Metamaterials: Design, Characterization and Applications
… to subdiffraction resolution with optical imaging. Fabricating a smooth silver superlens (0.6nm root mean square roughness) with 15nm thickness, I demonstrate 30nm imaging resolution or 1/12th of the illumination wavelength (near-ultraviolet), far below the diffraction-limit. Moreover. I …
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Fluorescent materials for short-wave infrared imaging
… their transformations over time. Fluorescence imaging is one of the most transformative technologies of modern biomedical imaging as it provides a low cost, high sensitivity method for real-time molecular imaging in vivo. As the scattering and absorption of light through biological tissue …
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Rapid time-resolved brain imaging with multiple clinical contrasts using wave-shuffling
Magnetic Resonance Imaging (MRI) is a non-invasive but slow biomedical imaging modality that produces images of multiple desirable contrasts. Currently, multiple receive channels are used in MRI to exploit redundancy and sample fewer data points for faster acquisition. Wave-CAIPI is a recently …
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Toward Controllable and Robust Surface Reconstruction from Spatial Curves
… as industrial prototyping, artistic design and biomedical imaging. While the problem has been widely studied for years, challenges remain for handling different type of curve inputs while satisfying various constraints. We study studied three related computational tasks in this thesis. First, we …
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Model-based quantitative combinatorial optical microscopy for extracting clinical imaging biomarkers
… recent years, many noninvasive, high-resolution biomedical optical imaging techniques based on unique, yet complementary, contrast mechanisms have emerged. While each imaging modality is able to elucidate certain properties of the particular sample under study, an integrated approach in which all …
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Design and manufacture of an ultra-high field ex vivo coil assembly
… in vivo (1) (2). The optimization of ex vivo imaging requires the design and construction of special purpose instrumentation. This thesis presents the mechanical design and construction of a 32 channel ex vivo coil assembly for use in a 7 tesla MRI. The unit will be used for research at the …
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Micro cameras as adjunct tools in biomedical applications
Biomedical imaging is one of the most impactful periprocedural tools and is used across a wide range medical applications. The eyes of the clinician are a key component in surgical decision making, and an image is often the first step in both diagnostic and interventional procedures. With the …
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