Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 278 for “"biological samples"”.
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Scheduling of biological samples for DNA sequencing
In a DNA sequencing workflow, a biological sample has to pass through multiple process steps. Two consecutive steps are hydroshearing and library construction. Samples arrive randomly into the inventory and are to complete both processes before their due dates. The research project is to decide the …
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Neutron Activation Analysis of Zinc in Biological Samples
Although zinc in biological samples has been determined previously by neutron activation analysis, the methods have been time consuming and involve post irradiation separations with remote control handling. Banks, et al, has developed a procedure involving 28 hours of reactor time and remote …
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Advanced Fluorescence Lifetime Imaging and Spectroscopy Techniques for Biological Samples
Intracellular viscosity is correlated with cause of diseases, and it also affects the metabolism and chemical signalling. In this thesis, fluorescence-based studies were conducted on a fluorescent molecular rotor, BODIPY-Ci2, which was used to measure the intracellular viscosity. BODIPY-C12 is …
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Characterization of Glycans Derived from Biological Samples Using LC-MS/MS
… are intricate compounds that play vital roles in biological activities. One of the most prevalent post-translational modifications (PTMs) is protein glycosylation, which enhances several biological functions, such as protein stability, localization, cellular communication, inflammation, immune …
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An investigation of Arsenic in biological samples from unexposed volunteers in the UK
… studies on the analysis of arsenic (As) in human biological samples, mainly urine but also hair and fingernails using inductively coupled plasma mass spectrometry (ICP-MS) and graphite furnace atomic absorption spectrometry (GF-AAS). The relationship between ethnicity and arsenic metabolism was …
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Use of solid-phase microextraction to detect semiochemicals in synthetic and biological samples
… (chemical messengers) in both synthetic and biological samples. Solid-phase microextraction, an alternative to traditional sample fractionation, employs specialized polymer fibers to detect molecules in a sample’s headspace. Solid-phase microextraction was previously used in the fields of …
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Evaluation of collection protocols for the recovery of biological samples from crime scenes
… recovery rate and stability of the DNA bearing samples. The main objective of this research was to improve the efficacy of the processes of collection and storage up to the point where the evidential material is received at a laboratory. The effect of heat and time post-collection on degradation …
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Nanolithography and nanoscopy methods for the study of biological samples in confined spaces
… protein tau in inclusion of Alzheimer brains samples, research has focussed on how amyloids form and their biological relevance in neurodegenerative diseases. Microfluidics are a well-established tool for the study of protein aggregation in a controllable environment, whereas super-resolution …
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Highly multiplexed molecular mapping of biological samples via integrated experimental and computational technologies
… and labeling of diverse molecular identities in biological samples has traditionally come at a price of decreased spatial information. Electron microscopy, with its nanometer spatial resolution and excellent ultrastructure preservation, yet essentially no molecular identification, is the most …
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Phenotypic and Metabolic Profiling of Biological Samples in Near Real-Time Using Raman Spectroscopy
… analytical methods for monitoring living biological systems will enable study of the physiological changes associated with growth, genetic manipulations, and adverse environmental conditions. Most existing analytical methods (NMR exempt), though highly accurate, must be performed off-line …
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Stability of drugs and pesticides of forensic toxicological interest and their metabolites in biological samples
Loss of analyte from biological samples during the post-mortem interval or during storage has potentially serious implications in forensic toxicology and represents a challenge for the forensic toxicologist, especially in the interpretation of case results. The initial aim of the studies in this …
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The Use of Spectral Imaging to Reveal Inorganics and Organics Identity in The Biological Samples
… (NPs) in fixed, living cells and tissue samples. We discovered that SI has a tremendous potential to study NPs localization and identification in biological samples at a single living cell and tissue, based primarily on the spectra information. In addition, we revealed for the first time …
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The Use of Mass Spectrometry for the Analysis of Biological Samples From Macro- and Microorganisms
MALDIMS was also used to analyze a potential CE sample, the egg layer hormone (ELH) of Aplysia. Various membranes were used as substrates for the analysis in addition to the stainless steel target. An excellent detection limit of 500 fmol was obtained using hydrophobic membranes.
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Rapid Two-Photon Holographic Scan Microscopy with Individual Quantum Dots and Its Applications in Biological Samples
… is particularly advantageous for imaging biological specimens since it offers reduced scattering, deep sample penetration, and intrinsic confocality when excited with point excitation. Here we report the first 2-photon microscopy of individual quantum dots in biological environment. …
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The application of direct electroanalytical techniques to the analysis of organic species in industrial and biological samples
… for the analysis of research, industrial and biological samples, are introduced.
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Design of a multi-sensor platform for integrating extracellular acidification rate with multi-metabolite flux measurement for small biological samples
To view the abstract, please see the full text of the document.
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Detection and Quantification of Single-walled Carbon Nanotubes in Environmental and Biological Samples for Evaluation of Fate, Transport and Bioaccumulation
… NIRF is highly sensitive to detect SWCNT in biological tissues due to the low fluorescence in the near infrared region from biological samples. Two exposure routes were investigated using NIRF: ingestion from dietary track using fathead minnow (FHM) fish model in an aquatic environment and …
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Synthesis & retention mechanisms of novel mixed mode stationary phase for detection of specific polar low molecular weight biological samples
The thesis primarily reports the synthesis, characterization and application of novel mixed mode stationary phases for Hydrophilic Interaction Liquid Chromatography (HILIC). HILIC is a rapidly emerging chromatographic mode that is finding great applicability in the analysis of polar organic …
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