Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"biological modeling"”.
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Bioastronautics: Biological Modeling of the Neural Response to Space Radiation and its interaction with Alzheimer's Disease Risk Genes
… work develops approaches to improve both the biological fidelity and the irradiation fidelity of these model systems with the overall goal of creating better tools for investigating the long-term neural consequences of radiation exposure.
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Computational Software for Building Biochemical Reaction Network Models with Differential Equations
… differential equations. Although developing new biological ideas is more of an art than a science, constructing a mathematical model from a biological idea is largely mechanical and automatable. This dissertation describes the practices and processes that biological modelers use for modeling and …
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Correlation-based Linking of Epigenomic Regions to Target Genes in Bulk and Single Cell Epigenomic Data
… sequencing has catalyzed a significant shift in biological modeling and hypothesis generation. In this study, we present advanced algorithms that utilize multiple modalities for peak-gene linking via correlation-based mechanisms. This approach provides a robust framework for bias correction and …
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Geographical assessment of algal productivity and water intensity across the United States
… biomass through a dynamic integrated thermal and biological modeling framework. Water demands were calculated through a validated dynamic thermal model which predicts temperature with an accuracy of -0.96 ± 2.72 °C and evaporation losses with a 1.46 ± 5.92 % annual accuracy. The biological model …
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Optimization of Biological Nitrogen Removal From Fermented Dairy Manure Using Low Levels of Dissolved Oxygen
… nitrifying kinetic parameters in BioWin®, a biological modeling simulator, which indicated the presence of a nitrification inhibitor in fermented dairy manure. Furthermore, an N balance during the aerobic zone indicated that simultaneous nitrification-denitrification (SND) was occurring in …
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Vertical fluxes in the upper ocean
… Vertical nutrient flux is maximum when the biological timescale of phytoplankton growth matches the vertical velocity frequency. Export of organic matter from the surface and the interior requires water parcels to cross the mixed layer base. Using Lagrangian analysis, we study the dynamics …
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Vertical Fluxes in the Upper Ocean
… Vertical nutrient flux is maximum when the biological timescale of phytoplankton growth matches the vertical velocity frequency. Export of organic matter from the surface and the interior requires water parcels to cross the mixed layer base. Using Lagrangian analysis, we study the dynamics …
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Parameter Identifiability and Estimation in Gene and Protein Interaction Networks
The collection of biological data has been limited by instrumentation, the complexity of the systems themselves, and even the ability of graduate students to stay awake and record the data. However, increasing measurement capabilities and decreasing costs may soon enable the collection of …
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Observational Intelligence: An Overview of Computational Actual Entities and their Use as Agents of Artificial Intelligence
This thesis' focus is on the use of Alfred North Whitehead's concept of Actual Entities as a computational tool for computer science and the introduction of a novel usage of Actual Entities as learning agents. Actual Entities are vector based agents that interact within their environment through a …
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The Importance of Dna Repair Capacity to (And A Model to Predict) Cell Radiosensitivity to Ions
… depth-dose distributions, greater relative biological effectiveness (RBE) and a lesser dependence on a number of biological factors known to affect radiosensitivity to photons, including DNA repair capacity. Thus, it is expected that an additional benefit of using ions is that they mitigate …
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The effects of environmental factors on honey bee morbidity
… Third, I provide a demonstration of how the biological modeling of environmental factor effects on honey bee health can be used by beekeepers to make cost-effective treatment decisions. I take an interdisciplinary approach to tackling these objectives drawing on methods from epidemiology to …
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Modeling Proton Relative Biological Effectiveness Using Monte Carlo Simulations of Microdosimetry
… is also known to offer an enhanced relative biological effectiveness (RBE) compared to photons. In the current clinical standard, RBE is fixed at 1.1 at all points along the proton beam, meaning protons are assumed to require 10% less dose than photons to achieve target coverage and organ at …