Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 202 for “"biological effects"”.
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The Biological Effects of Novel Synthetic Retinoids
… and that these isomers have different biological activity. Due to this EC23 and EC19, synthetic analogs of these retinoids which are not able to be isomerised, have been synthesized. These two compounds until now have not been tested in vivo. We showed that both EC23 and EC19 are able …
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Purification, detection and biological effects of cyanobacterial toxins.
… toxins were also employed to investigate the effects of microcystins on plants. Bioassay methods revealed the inhibitory effects of microcystins on plant growth and development. The accumulation of microcystins in exposed plants was then investigated. A simple plant model lacking roots was …
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Biological effects of trogocytosis on CD4+ T lymphocytes
… the immunological synapse. The mechanism and biological significance of this process, termed trogocytosis, is still unclear. In this thesis I examined the impact that trogocytosis has on the individual T cell after capturing molecules from the antigen presenting cell. I employed murine …
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Biological effects of trogocytosis on CD4+ T lymphocytes
… the immunological synapse. The mechanism and biological significance of this process, termed trogocytosis, is still unclear. In this thesis I examined the impact that trogocytosis has on the individual T cell after capturing molecules from the antigen presenting cell. I employed murine …
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High-Throughput Mapping of The Biological Effects of Particle Therapy
… linear energy transfer (LET) specific relative biological effectiveness (RBE) when compared to photons. It is essential to employ accurate biophysical models for particle beams in order to maximize the therapeutic potential of particle therapy through the introduction of biologically optimized …
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Investigating the biological effects of (nano)particles in Alzheimer’s disease pathologies
… fields, also highlighting the cytotoxic effects from overuse as a biomedicine and its potential implication in neurodegeneration and AD as an air pollutant. Subsequently, chapter 4 explored the biological effects that air pollutants (iron, diesel and magnetite) have on AD pathologies. …
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Development of Lineal Energy Spectrum-Based Biological Effects Models for Protons
… mathematical formulation of a mathematical radiobiological model for the prediction of the biological effects of protons began. Using previously gathered clonogenic cell survival response data of H460, H1437, U87, and AGO cell lines following proton irradiation, mathematical models describing the …
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Biological effects of the ingestion of the toxic plant, Cycas circinalis
Thesis (M.S.)--Michigan State University. Dept. of Foods and Nutrition, 1964
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The biological effects of artificial reefs in Smith Mountain Lake, Virginia
… the summer and fall of 1973 to evaluate the biological effects on the aquatic ecosystem. Virtually all sport fishes were attracted to the reef areas. The frequency of sport fish on the reefs generally coincided with their overall abundance in the reservoir. Sunfishes (Lepomis spp.) and white …
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Using Heterogeneous Information Sources for Understanding and Predicting Biological Effects of Compounds
Understanding a compound’s biological effects such as its Mechanism of Action (MoA) and safety profile is a challenging task in drug discovery process. However, this understanding can facilitate drug discovery process and provide an early warning for potential risks. Biological effects …
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Irradiators for measuring the biological effects of low dose-rate ionizing radiation fields
Biological response to ionizing radiation differs with radiation field. Particle type, energy spectrum, and dose-rate all affect biological response per unit dose. This thesis describes methods of spectral analysis, dosimetry, biological assays, and mathematical modeling for determining the …
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The biological effects of HIV-1 Nef on the development of B-cell Lymphoma
… that the virus can have direct oncogenic effects, often through the action of specific virally-encoded proteins. The latter can act alone or collaboratively with cellular proteins, as well as with oncoproteins of established oncogenic viruses such as the Kaposi's Sarcoma-associated Herpes …
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Shedding Light on the Biological Effects of Ionising Radiation on DNA Using Advanced Optical Microscopy
Detrimental effects of ionising radiation (IR) stem from its unique ability to produce clustered DNA damage (CDD) and double-strand breaks (DSBs). CDD consists of two or more lesions in close proximity, including DSBs, single-strand breaks and/or base damages. CDD complexity increases with rising …
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Investigating the Biological Effects of Rosemary (Rosmarinus officinalis L.) Extract on Skeletal Muscle Glucose Uptake
… to decrease blood glucose levels but its effects on SKM are not known. We hypothesized that RE acts directly on SKM to increase glucose uptake (GU). We found an increase in GU (184±5.07% of control, p<0.001) in L6 myotubes by RE to levels similar to insulin and metformin. Carnosic acid …
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Some physical, chemical, and biological effects of heavy poultry manure applications on a soil ecosystem
… near 10 times (57 cm/ha) that on the controls. Effects on the soil biology were pronounced but complex. The most probable numbers of Nitrosomonas sp. were 100 times higher on the manured plots in spring. Nitrobacter sp. numbers were less affected by manure. Soil respiration in samples taken in …
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Physiological, Biochemical, and Molecular Biological Effects of +4⁰C Acclimation on the Antarctic Teleost Trematomus bernacchii
… previously reported in T. bemacchii gill. The effects of +4°C acclimation were investigated by measuring serum osmolality, oxygen consumption, substrate concentration dependent activation of the Na+,K+- ATPase, and ouabain inhibition of phosphoenzyme intermediate formation. Acclimation to +4°C …
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Investigation of the Biological Effects of Rosemary (Rosmarinus Officinalis L.) Extract in Human Lung Cancer Cells
… (RE) has been reported to have anticancer effects in vitro and in vivo however, limited evidence exists regarding the effects of RE and its polyphenolic constituents carnosic acid (CA) and rosmarinic acid (RA) in lung cancer. The present study shows RE, CA and RA inhibit lung cancer cell …
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Biological effects of bioactive components and extracts derived from edible plants commonly used in human nutrition
… PhD research project was the evaluation of the biological effects of bioactive compounds derived from edible plants, with particular attention on their possibility to counteract oxidative damage and inflammation. After a preliminary study of in vitro antioxidant activity, regarding the …
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