Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 143 for “"bioimaging"”.
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Fluorescent silicon nanocrystals for bioimaging
… potentially interesting for in vitro and in vivo bioimaging. Here, Si nanocrystals are studied for imaging applications. The stability of Si nanocrystal dispersibility and photoluminescence (PL) in aqueous solutions was studied. Hydrophobic Si nanocrystals were dispersed with surfactants to …
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Bioimaging with photonic crystal enhanced microscopy
… great promise to the label-free biosensing and bioimaging. Future work will extend the application of PCEM to broader research and application fields served as the next generation sensing modalities.
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Advancing fluorescence lifetime microscopy for quantitative bioimaging
This thesis presents the development of fluorescence lifetime imaging microscopy (FLIM) methodologies to advance biological understanding of neurodegeneration and stem cell differentiation. Two FLIM technologies enabling faster FLIM acquisition were developed and tested for high-throughput …
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Photonic Crystal Enhanced-Fluorescence and Label -Free Bioimaging
In further work, a theory is outlined for predicting photonic crystal label-free imaging resolution based on resonance spectral characteristics. Devices are characterized by patterning a resolution standard onto the sensor using photolithography, and excellent design control over label-free imaging …
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Bioimaging of animal embryogenesis: mathematical methods and computational algorithms
Some fundamental biological processes such as embryonic development have been preserved during evolution and are common to species belonging to different phylogenetic positions, but are nowadays largely unknown. The understanding of cell morphodynamics leading to the formation of organized spatial …
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SYNTHESIS OF NOVEL BODIPY LIBRARIES AND THEIR APPLICATION IN BIOIMAGING
The need for recognizing and sensing environmentally and biologically important species has leaded large efforts towards sensor development. We first applied a combinatorial approach to construct diversity-oriented fluorescent libraries as chemical tool box based on BODIPY fluorophore. These novel …
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Photophysics of Organic Probes and their Applications in Bioimaging & Photodynamic Therapy
… (3D) images, is now being widely employed for bioimaging. This dissertation focuses on the design, synthesis, and photophysical characterization of new fluorophores, as well as desirable applications. Chapter 1 gives an account of a brief introduction of luminescence and 2PA, as well as their …
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Boron Functionalization of BODIPY Dyes, and Their Evaluation as Bioimaging Agents
… oxygen nucleophiles for further investigation as bioimaging agents. Chapter 1 of this dissertation describes an overview of BODIPYs including synthetic development, post-synthetic functionalization strategies, and how BODIPYs can be involved in many biological applications. Chapter 2 discusses the …
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Synthesis of diene ligands with H-bonding capabilities for bioimaging applications
Investigations of the synthesis of novel bioprobes (Scheme A), potentially useful in bioreactions and sugar sensing, are described. A preliminary study is reported that aims to validate the feasibility of tricarbonyl iron complexes and their derivatives in applications as a constituent part of …
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BioLaser: Establishing a High-Resolution Laser Ablation Tomography Platform for UK Bioimaging Research
High-resolution 3D tomographic imaging of botanical materials can provide enormous insight into questions regarding relationships between structure and function. The National Institute for Agricultural Botany (NIAB) sponsored this body of work to meet an unfilled imaging niche for a tomographic …
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Synthesis and Characterization of New Probes for use in Fluorescence and X-ray CT Bioimaging
The pursuit of more suitable drugs intended for possible biological applications are a continuously growing topic of research within the scientific community. One of these suitable qualities includes the need for hydrophilicity and or some appropriate delivery system for the drug to enter into …
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Advancement of fiber image guide based snapshot imaging spectrometer technology for bioimaging and environmental applications
Hyperspectral imaging spectrometers provide detailed and continuous spectral data in addition to spatial information found in commercial RGB or monochromatic cameras. The addition of spectral information can provide valuable insight in many fields such as but not limited to biomedical imaging, …
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Sviluppo e ottimizzazione di tecniche di bioimaging ad alta risoluzione spaziale basate su strategie di rilevamento innovative
La microscopia confocale e la microscopia a super-risoluzione, note anche come microscopia a scansione di immagini (ISM), sono due potenti strumenti per l'imaging ottico ad alta risoluzione, ampiamente utilizzati nella ricerca biomedica. Tuttavia, entrambe le tecniche sono soggette a limitazioni di …
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Advancing Clinical Remission in Severe Asthma: Efficacy of a Comprehensive Management Strategy Guided by Airway Inflammometry and Bioimaging [Migliorare la remissione clinica nell'asma grave: Efficacia di una strategia di gestione completa guidata dall'infiammometria delle vie aeree e dal bioimaging]
… respiratoria, infiammometria delle vie aeree e bioimaging. La remissione clinica è stata definita come assenza di riacutizzazioni per 24 mesi, assenza di utilizzo di corticosteroidi orali (OCS), e sintomi parzialmente/ben controllati, con o senza criteri di funzionalità respiratoria. …
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Cyclometallated platinum and iridium complexes with thiolate ligands, and novel bioimaging agents inspired by dynamic disulfide interchange reactions
… for use in chemosensing applications and as bioimaging agents. This final topic is an area of increasing study as a result of the diverse and tuneable excited states of such molecules, and their advantages over conventional organic emitters such as reduced photobleaching and long luminescence …
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Design, Synthesis, and Characterization of Glycodendrons Through Small Molecule and Linear Polymer Models
… of near infrared (NIR) fluorophores for bioimaging applications. A design of experiments was used with small molecule model compounds to determine the parameters for successful thiol-ene click reactions that would lead to success of more complicated amphipathic polymer-polymer coupling …
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Optical properties and biological applications of fluorescent gold nanoclusters
… the potential application in biosensing and bioimaging. Fluorescence anisotropy spectroscopic study confirmed the bio-chemical activities of BSA in BSA-AuNCs, demonstrating a new possibility of using BSA-AuNCs as fluorescence probe. And the bioimaging study of BSA-AuNC in intestine sections …
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