Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 319 for “"biofilm formation"”.
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Biofilm Formation by Moraxella Catarrhalis
This is the first detailed study of biofilm formation in vitro by the Gram-negative bacterial pathogen Moraxella catarrhalis. Growth of M. catarrhalis in a continuous-culture biofilm system resulted in little detectable change in outer membrane protein production compared to broth-grown M. …
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Biofilm formation on metal surfaces
The development of biofilms on mild and stainless steel surfaces in pure and mixed batch cultures of the bacterial species Pseudomonas fluorescens and Desulfovibrio desulfuricans and the role of these biofilms in corrosion of steel has been investigated. Early events leading to the formation of …
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Biofilm formation and virulence of Streptococcus pneumoniae
… determinants of distinct virulence phenotypes. Formation of biofilms is an important step in pneumococcal pathogenesis, as they serve as reservoirs of infection and organisms within biofilms are resistant to antimicrobials and host immune defences. The aim of this work was to extend our …
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Shigella Boydii 18: Characterization and Biofilm Formation
… cells. Shigella boydii may be forming a biofilm on the surface of the parsley, which may explain why produce wash is effective against S. boydii planktonic cells, but ineffective against S. boydii on parsley. Scanning electron micrographs and environmental scanning electron micrographs …
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Effects of Surface Topography on Bacterial Biofilm Formation
<p>Biofilms are multicellular structures with bacterial cells attached to a surface and embedded in an extracellular matrix. With high-level resistance to antimicrobial agents, biofilms are the cause of chronic infections associated with implanted medical devices such as breast implants, orthopedic …
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Effects of substrate stiffness on bacterial biofilm formation
<p>Biofilms are communities of microbial cells attached on surfaces and embedded in a self-produced extracellular matrix comprised of polysaccharides, DNA, and proteins. Biofilms of pathogenic bacteria cause serious chronic infections due to high tolerance to antibiotics and host immune systems …
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PATTERNED BIOFILM FORMATION TO INVESTIGATE BACTERIA-SURFACE INTERACTIONS
<p>Bacterial adhesion to surfaces and subsequent formation of microcolonies play important roles in biofilm formation, which is a major cause of chronic infections and persistent biofouling. Despite the significance, mechanistic understanding of biofilm formation is still hindered by the structural …
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Molecular Engineering Approaches against Germs, Spores and Biofilm Formation
… future anti-virulence small molecules against biofilm formation. This dissertation is thus divided into these three sections accordingly: Traditional zwitterionic polymers have been widely accepted and routinely applied because of their biocompatibility and nonfouling property. However, less …
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Controlling Microbial Colonization and Biofilm Formation Using Topographical Cues
… cell–cell interactions during the evolution of biofilms. I investigated the adhesion, colonization, and biofilm formation of the opportunistic human pathogen Pseudomonas aeruginosa on a solid coated in close-packed spheres of polystyrene, using flat polystyrene sheets as a control. The results …
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Characterization of adherence, cytotoxicity and biofilm formation by Gardnerella vaginalis
… demonstrated that G. vaginalis forms an adherent biofilm on the vaginal epithelium of women with BV. Furthemore, evidence suggests that the high rate of recurrence associated with BV is related to incomplete eradication of the biofilm. The overall goal of this study was to characterize G. …
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Identifying Novel Factors Involved in Biofilm Formation by Vibrio Fischeri
<p>Biofilm formation by bacteria provides them with a means to survive harsh environmental conditions and promote colonization of a particular surface (biotic or abiotic). Due to the resistance properties of biofilms, biofilm-forming bacteria are difficult to treat in the context of host …
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Post-translational control of <em>Bacillus subtilis</em> biofilm formation
A biofilm is a complex community of cells enveloped in a self-produced polymeric matrix. Entry into a biofilm is exquisitely controlled at the level of transcription and in Bacillus subtilis it requires the concerted efforts of several major transcription factors including the repressor SinR and …
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Probing topographical influences on biofilm formation using dynamic-mask multiphoton lithography
… that the complexity and heterogeneity of the biofilm mode of bacterial existence has been widely appreciated. Biofilms have persisted for billions of years as social communities of cells aggregated and attached on surfaces, and today they are both necessary and harmful within the human body …
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Role of Exopolymeric Substances in Biofilm Formation on Dairy Separation Membranes
… and affects product quality. The growth of biofilms on membranes contributes to biofouling. Biofilms are very difficult to eliminate, and will serve as the seed for additional biofilm development and product contamination. The biofilm matrix is composed mainly of microbial exopolymeric …
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Investigation of molecular mechanisms of biofilm formation by <i>Listeria monocytogenes</i>
A biofilm is a state where bacteria are attached to a surface to form sessile communities. Cells in the sessile communities have a higher tolerance to antibiotics and sanitizers. Correspondingly, the persistence of bacteria can lead to infections and outbreaks of foodborne diseases. Listeria …
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Listeria monocytogenes in the mushroom production environment: biofilm formation and control measures
… has been attributed to its ability to form biofilms. However, prior to this work, the biofilm forming ability of L. monocytogenes on mushroom industry relevant surfaces was undetermined. Furthermore, the mushroom industry generally employs the use of biocides that are specifically marketed …
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Streptococcal colonization of host mucosal surfaces: a study of biofilm formation and dispersal
… Experimental evidence suggests that GAS forms biofilms during the colonization of a surface. A biofilm is a bacterial sessile community encased in an extracellular matrix and attached to a substratum or interface. Biofilms are inherently tolerant to host defenses and antibiotic therapies and …
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