Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 518 for “"biocompatibility"”.
-
Biocompatibility Investigations of Surgical Implant Alloys.
Three alloys used for surgical applications, 316L stainless steel (Fe-Cr-Ni, ASTMF138), Co-Cr-Mo (ASTM F75) and T1-6A1-4V (ASTM F136) were investigated to determine the elemental constituents released during corrosion and to determine the tissue responses elicited under in vitro and in vivo …
-
The biocompatibility and characterization of aromatic thermosetting copolyester
… bone substitutes or scaffolds focus on achieving biocompatibility and sufficient mechanical properties. In this thesis, we investigated the biocompatibility of synthetic polymers called aromatic thermosetting copolyesters (ATSP) as potential biomaterials for bone replacements (implants). These …
-
Biocompatibility of an implantable ophthalmic drug delivery device
… delivery to the eye wall. To investigate the biocompatibility of this solution, test devices containing gears or a ball bearing were designed to mimic elements of its moving parts, geometry and materials. Cell culture studies identified a polytetrafluoroethylene filter with 100m pores as a …
-
Biocompatibility and Bioactivity of Calcium Silicate-based Dental Bioceramics
… cost.<br/><br/>This in vitro study looked at the biocompatibility of Biodentine (a new tricalcium silicate formulation), comparing it to the original tricalcium silicate material ProRoot MTA. The study used gingival and periradicular fibroblast cell cultures, with both direct and indirect material …
-
Polyethylene glycol copolymer nanocarriers: Biocompatibility, uptake and intracellular trafficking in neurons
… nanocarrier (PE-MNC) and was tested for its biocompatibility in a neuron model (PC12 cells), as well as in chick dorsal root ganglion (DRG) sensory neurons, cells that are damaged during SCI. We have performed time- and dose-dependent studies showing that treatment of up to 150 µg/mL PE-MNC …
-
Biocompatibility assessment of a sol-gel modified electrospun ventricular shunt catheter
Hydrocephalus is a clinical condition that usually originates froma reduced passage of cerebrospinal fluid from one brain ventricle toanother. The main procedure to treat this condition involves the insertion of a shunt catheter to bypass the blockage and allow the CSFto flow from the ventricles, …
-
Surface modification of traditional and bioresorbable metallic implant materials for improved biocompatibility
<p>Due to their strength, elasticity, and durability, a variety of metal alloys are commonly used in medical implants. Traditionally, corrosion-resistant metals have been preferred. These permanent materials can cause negative systemic and local tissue effects in the long-term. Permanent stenting …
-
In vivo activation and biocompatibility of a MEMS microreservoir drug delivery device
Temporal and spatial control over the delivery of therapeutic compounds is an important, fertile, and rapidly advancing field of study in medicine. This work describes the advancement of a new technology of drug delivery from a benchtop prototype releasing tracer molecules to an implantable device …
-
Preparation and Biocompatibility of Electrospun Zwitterionic Poly(Sulfobetaine Methacrylate) for Wound Dressing Applications
Poly(sulfobetaine methacrylate) (PSBMA) can be potentially utilized in filtration and wound dressing applications for which nanofibers structures are highly desirable. In this work, a series of PSBMAs with different molecular weights were synthesized, characterized, and electrospun into nanofibers. …
-
Evaluation of the antimicrobial properties and biocompatibility of polypropylene mesh conjugated with gold nanoparticles
… hernia repairs and for pelvic slings. However, biocompatibility and infection rates are a concern. Conjugating gold nanoparticles (AuNPs) to PP mesh may enhance biocompatibility while reducing infection rates. In this study we investigated the size and concentration of gold nanoparticles …
-
A study investigating the mechanical testing of a novel dental restorative material and its biocompatibility
… The current study investigates the strength and biocompatibility of three Resin Based Composites (RBCs); Ormocer Admira (VOCO, Cuxhaven, Germany), dimethacrylate FiltekTMZ250 (St Paul, MN, US) and a novel RBC namely X-tra Fil (VOCO, Cuxhaven, Germany). These materials were tested using bi-axial …
-
Design of <i>In Vivo</i> Assays for Study of Transport, Biocompatibility and Toxicity of Nanoparticles
… <em>in vivo</em> assays for study of transport, biocompatibility and toxicity of nanoparticles (NPs) in zebrafish embryos. We synthesized and purified spherical silver (Ag) NPs with diameters, ranging from 12 to 95 nm, that are stable (non-aggregated) in egg-water media. We developed new imaging …
-
PECVD of silicon and titanium based coatings to enhance the biocompatibility of blood contacting biomedical devices
… on various factors including the design and biocompatibility of the biomaterial, surgical procedure adopted, injuries made during implantation and health and condition of the patient. The success of a biomaterial depends on the interaction and the progressive reaction between the blood …
-
A Comparative Analysis of the Neurochemical Properties of Olfactory Ensheathing Cells and their Biocompatibility in Various Biomatrices
Olfactory ensheathing cells (OECs) are the chief glial population of the mammalian olfactory nervous system and are thought to be responsible for the successful directional growth of new olfactory axons throughout the life of adult mammals. Due to this unique property, OECs have been targeted as a …
-
Elucidating strategies to design tailored chitosan surfaces with enhanced antibiofouling and biocompatibility properties via plasma assisted processes
… treatment and bioengineering. Due to its unique biocompatibility, biodegradability and antibacterial properties, chitosan has sparked attention as a material for biomedical applications. The antimicrobial properties of silver have been well-known for centuries, and its derivatives were being used …
-
Improving Biocompatibility By Controlling Protein Adsorption: Modification And Design Of Biomaterials Using Poly(Ethylene Glycol) Microgels And Microspheres
Guided by the clinical needs of patients and developments in biology and materials science, the primary focus of the biomaterials field remains at the solid/liquid interface between biomaterial surfaces and biological fluids. For blood-contacting devices, biological responses are initially elicited …
Page 1 of 26