Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 102 for “"biochemical reactions"”.
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Mechanisms of biochemical reactions within crowded environments
… gene regulation, and protein folding. Thus, biochemical reactions that take place in such crowded conditions differ from diluted test tube conditions, and a considerable effort has been invested in order to understand such differences. In this work, we combine different computationally tools …
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A COMPUTATIONAL STUDY ON BIOCHEMICAL REACTIONS OF SULFUR-CONTAINING COMPOUNDS
… thesis reports on the computational studies of biochemical reactions in two sulfur-containing systems: (1) DNA methylation by the DNA methyltransferase via nucleophilic addition of a Cysteine thiol and methyl transfer from SAM to cytosine; (2) H2S release from the reaction of a free thiol and …
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A hybrid algorithm for the simulation of biochemical reactions and diffusion
… on the number of particles N: For n-order reactions, the asymptotic runtime is proportional to N^n for exact algorithms, but proportional to N^(n-1) for COAST. So clearly, COAST provides significant improvements, in particular if N is large and n is small.
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Comparison of Micrscan Identification and Susceptibility Testing Methods for Streptococcus Dysgalactiae to Conventional Biochemical Reactions and Kirby-Bauer Susceptibility Testing Methods
… infections was used to evaluate and compare the biochemical reactions of the gram positive Combo Type 6 panel on the MicroScan autoSCANR system to a conventional procedure for identification of streptococci. Of the 100 isolates, 83.3% was identified as "Very Rare Biotype" by the MicroScan and …
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Polymer-Based Microfluidic Devices for High Throughput Single Molecule Detection: Applications in Biological and Drug Discovery
… is a viable platform for parallel processing of biochemical reactions to increase data production rates due to its ability to generate fluidic networks with a high number of processors over small footprints suitable for optical imaging. Single-molecule detection (SMD) is another technology which …
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Metabolic engineering analysis of post-burn hepatic hypermetabolism
… properties through the modification of specific biochemical reactions or introduction of new ones with the use of recombinant DNA technology. It has been used to investigate and modify intermediary metabolism in a variety of microbial organisms of biotechnological interest. An emerging area of …
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Identification of novel properties of metabolic systems through null-space analysis
… description of the complex network of biochemical reactions that sustain life. Among these, genome-scale models capture the entire metabolism of an organism, by encompassing all known biochemical reactions encoded by its genome. They are invaluable tools for exploring the metabolic …
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The dynamics of metabolic regulation
Cellular metabolism is a complex network of biochemical reactions, whose regulation enables living cells to cope with variable environments and perturbations. Since metabolic regulation occurs at multiple time scales and involves diverse molecular mechanisms, understanding and manipulating the …
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ΚΑΤΑΝΟΜΗ ΒΙΟΤΥΠΩΝ ΚΑΙ ΟΡΟΤΥΠΩΝ ESCHERICHIA COLI ΣΕ ΚΛΙΝΙΚΑ ΥΛΙΚΑ. ΣΥΣΧΕΤΙΣΗ ΦΑΙΝΟΤΥΠΩΝ ΑΝΤΙΣΤΑΣΕΩΣ ΚΑΙ ΟΡΟΤΥΠΩΝ
… FOR THE CLASSIFICATION TO BIOTYPES, 25 BIOCHEMICAL REACTIONS WERE USED. SEROTYPING WAS PROCESSED WITH 36 MONOVALENT ANTISERA WHILE SUSCEPTIBILITY TO ANTIBIOTICS WAS CARRIED OUT WITH THE USE OF STANDARDIZED 13 SINGLE DISC DIFFUSION METHOD. OUT OF 249 STRAINS, 179 WERE CLASSIFIED TO 23 …
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Monitoring and Inverse Dispersion Modeling to Quantify VOCs from MSW Landfill
… to anaerobic stabilization by bacteria. These biochemical reactions produce volatile organic compounds (VOCs) like methane and others. Due to heterogeneity in refuse composition, unpredictable distribution of favorable environmental conditions for bacterial actions and highly uncertain pathway …
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On the theory of Brownian aggregation in colloidal dispersions
… fluids, nanoparticle self-assembly, and biochemical reactions. The manipulation of colloidal dispersion stability by containing or promoting aggregation rates is manifest in several natural phenomena and engineering applications. The destabilization of silt dispersions as river water …
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Design and Synthesis of Thiamine Pyrophosphate (TPP) Analogues for Investigating the Structure-Activity Relationship (SAR) of Inhibitors of TPP-dependent Enzymes
… vary significantly in substrate preferences and biochemical reactions. To study these enzymes by chemical inhibition, the most popular way is to use thiamine/TPP analogues, which typically feature a neutral aromatic ring in place of TPP’s positive thiazolium ring. In response to the growing …
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The dynamics of enzymatic switch cascades
… model the 'effective collisions' picture of the biochemical reactions that constitute the network. Furthermore we measure the fidelity of the signaling process through the mutual information content between the output of a given switch and the original environmental input to the system. We find …
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Kinetic modeling and experimentation of anaerobic digestion
… rely on simple algebraic equations instead of biochemical reactions, or consider so many external parameters that they become overly complicated and require much input information and computation time. This work provides an intermediate kinetic model that predicts biogas output over time with …
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Protonation and Membrane Protein Function
Many biochemical reactions are electrostatically driven. Titratable amino acids significantly contribute to the electrical forces that drive these reactions. The protonation state of a titratable residue embedded in a protein environment can differ from its default value in bulk water at neutral …
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A metabolic profiling approach to human disorders of energy metabolism
The integrated network of biochemical reactions known collectively as metabolism is essential for life, and dysfunction in parts of this network causes human disease - both rare, inherited disorders and common diseases such as diabetes mellitus. The study of metabolic disease depends upon …
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A model of the checkpoint response of the cell cycle of frog-egg extracts in the presence of unreplicated DNA
… process is regulated by a complex network of biochemical reactions. A core part of this network, called the "Cell Cycle engine" is evolutionarily conserved. The dimer of CDK1 (a protein kinase) and Cyclin proteins (the regulatory components), called M-phase Promoting Factor (MPF), and its key …
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Bifurcation Analysis of a Model of the Frog Egg Cell Cycle
… activity is regulated by a complex network of biochemical reactions. Novak and Tyson, and their collaborators, have been studying the qualitative and quantitative properties of a large system of nonlinear ordinary differential equations that describe the molecular details of this system as …
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Linking Heterotrophic Metabolism and Nutrient Uptake in Headwater Streams
… to metabolism based on the stoichiometry of biochemical reactions. The differences between these two groups of organisms confound straightforward regression approaches to quantifying the relationship between nutrient demand and metabolism at an ecosystem level. We address how nutrient demand …
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Acoustically-levitated drop reactor (ldr) employable for kinetics measurements of biochemical networks
… part of understanding the mechanisms of biochemical reactions. The typical means of studying such systems use stirred cuvettes, stopped-flow apparatus, microfluidic systems, or other small sample containers. These reaction-kinetics measurements reactors are usually made of quartz, glass, …
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