Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"biochemical models"”.
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Stochastic Simulation Methods for Biochemical Systems with Multi-state and Multi-scale Features
… stochastic modeling and simulation methods for biochemical systems. The thesis is focused on systems with multi-state and multi-scale features and divided into two parts. In the first part, we propose new algorithms that improve existing multi-state simulation methods. We first compare the well …
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Stochastic Simulation Methods for Solving Systems with Multi-State Species
… method for stochastic modeling and simulation of biochemical systems. However, its population-based scheme faces the challenge from multi-state situations in many biochemical models. To tackle this problem, Morton-Firth and Bray's stochastic simulator (StochSim) was proposed with a particle-based …
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Stochastic regulation of signaling in lymphocytes
… will be transmitted through a complex network of biochemical reactions underlying the cellular functions. Such a complex network is fundamentally regulated by stochastic principles with intriguing behaviors. This thesis aims to understand the signaling network in lymphocytes and the stochastic …
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Biochemical Analysis of Poly(ethylene terephthalate) Film Degradation Kinetics of Engineered IsPETase Variants
… is known about the surface reaction and how biochemical behavior might differ on a 2D solid surface compared to solution phase. Consequently, traditional solution-phase biochemical models, such as Michaelis-Menten, may not be directly applicable to kinetics of these enzymes, as the catalysis …
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Computational modeling of knowledge and uncertainty in systems biology for drug target identification and protein engineering
… systems biology, ordinary differential equation models are used frequently to model the dynamics of molecular and cellular systems. These models are parameterized with rate constants and other quantities that are often estimated from empirical data. When the data are insufficient to fully …
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Lanthanides and quantum dots : time-resolved laser spectroscopy of biochemical Förster Resonance Energy Transfer (FRET) systems
… Transfer (FRET) plays an important role for biochemical applications such as DNA sequencing, intracellular protein-protein interactions, molecular binding studies, in vitro diagnostics and many others. For qualitative and quantitative analysis, FRET systems are usually assembled through …
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The effect of influent organic compounds on the performance of biological nutrient removal systems
… proposed by Marais et al., 1983. The most recent biochemical models, proposed by Comeau et al., 1986 and Wentzel et al., 1986, were also tested using the data collected in the present investigation. Both models, in most cases, overestimated the ratios of phosphorus release to volatile fatty acid …