Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"bioactivity assessment"”.
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Biopeptides from food by-products: Production, fractionation and bioactivity assessment
Es bien conocida la importante generación de residuos de la industria alimentaria y la importancia de llevar a cabo procesos y desarrollar técnicas y usos finales de dichos sub-productos con el fin de avanzar hacia una industria alimentaria sostenible. En esta Tesis Doctoral se plantean procesos de …
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Phytochemical Investigation and Bioactivity Assessment of Medicinal Plant from Northern Nigeria
Boswellia dalzielii (Burseraceae) has ethnopharmacological importance and is claimed to have anti-infection and immunomodulatory effects. In the Northern part of Nigeria, a region with a tropical dry climate, an aqueous infusion of this plant is used in the treatment of infections and tumours. The …
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Bioactivity assessment of peptide QUB1471 from the skin secretion of the Chinese torrent frog (Amolops wuyiensis)
Amphibians have developed successful defensive strategies for combating predators and invasive microorganisms encountered in their broad range of living environments, which involves secretion of complex cocktails of noxious, toxic and diverse bioactive molecules from the skins. Since ancient times, …
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Identification and bioactivity assessment of a protease inhibitor QUB-1833 from the skin secretion of Lithobates catesbeiana
… in this study are isolation, identification, and bioactivity assessment of bioactive peptides from Lithobates catesbeiana skin secretions.<br/><br/>Using 'shotgun' cloning and DNA sequencing, the peptide sequences were obtained from secretions. Then, the peptide QUB-1833, whose amino acid sequence …
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Identification, isolation and bioactivity assessment of a novel peptide from the skin of Heilongjiang Brown Frog (Rana amurensis)
Skin and skin secretions play essential roles in amphibian’s lifecycle. The bioactive substance form skin secretions, various peptides or proteins, was considered as treasures in medical treatment. The mechanism of antimicrobial peptides (AMPs) on antimicrobial activities was different from …
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Identification, isolation and bioactivity assessment of a bioactive peptide QUB-1465 from the skin secretion of Hylarana guentheri
Amphibian skin secretions are a rich source of bioactive peptides, some of which can be developed as drug candidates. Among these natural peptides, AMPs have attracted much attention because of its potential to replace traditional antibiotics and solve the problem of microbial resistance as AMPs …
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The Structural Characterization and Bioactivity Assessment of Nonspecific Lipid Transfer Protein 1 (nsLTP1) from Caraway (Carum Carvi) Seeds
… for docking fatty acids against caraway nsLTP1. Assessment of nsLTP1 cytotoxic activity was achieved by MTS assay, and the Trolox equivalent antioxidant capacity (TAC) was determined. Secondary strucutre stability of nsLTP1 was examined by circular dichroism (CD) spectroscopy.</p> …
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Discovery and bioactivity assessment of a novel peptide from the skin secretion of the Senegal running frog Kassina senegalens
Frog skin is characterised with an abundance of biologically active antimicrobial peptides (AMPs) with a broad-spectrum effect against a variety of microorganisms. The contribution of their complex and diverse structures, physicochemical properties and mechanisms of biological activity, have been …
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Identification and bioactivity assessment of an antimicrobial peptide from the defensive skin secretion of the northern leopard frog, Rana pipiens
… antimicrobial peptide named Brevinin-1Pk. In bioactivity assays, this peptide was found to be significantly inhibitory to Gram-positive and Gram-negative bacteria and yeast (Staphylococcus aureus and Escherichia coli and Candida albicans, respectively.) at concentrations of 2 µM, 16 µM and 32 …
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Discovery and bioactivity assessment of a peptide, QUB-1976, from the skin secretion of the Senegal running frog, (Kassina senegalensis)
… divided into different types according to their bioactivity. Among all types of peptides, AMPs (antimicrobial peptides) are the most significant for their clinical value in infection therapy. <br/><br/>This study focused on a peptide isolated from the skin secretion of the Senegal running frog, …
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Discovery and bioactivity assessment of a peptide QUB-1331 from the skin secretion of the Senegal running frog (Kassina senegalensis)
Since more and more antimicrobial peptides exhibited enormous potency in inhibiting the growth of microorganisms, especially bacteria and fungi, they have been regarded as alternative therapeutic reagents for various treatments in clinic. <br/><br/>In this research, a novel peptide QUB-1331 …
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Molecular cloning and bioactivity assessment of a bioactive peptide QUB-1509 from the skin secretion of the Asian frog Hylarana guentheri
The abuse of antibiotics has resulted in the increase of drug-resistant bacteria and as numerous people have now died from super-bacterial infections worldwide, the quest for and development of novel antibiotics is urgent and significant. Temporins are among the smallest peptides that have been …
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Bioactivity assessment of a bioactive peptide, QUB-2022, isolated from the skin secretion of the tiger-striped leaf frog, (Phyllomedusa tomopterna)
Anurans, including frogs and toads, account for approximately 90 % of extant amphibian species. Most peptides secreted from the anuran skin have bioactive functions to prevent the invasion of microorganisms in their habitats.<br/><br/>In this study, a bioactive peptide belonging to the phylloseptin …
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Identification, isolation and bioactivity assessment of a novel peptide from the skin secretion of the Tiger-striped Leaf Frog (Phyllomedusa tomopterna)
… The purified peptide was used in a series of bioactivity tests. QUB-2982 displayed antimicrobial activities towards E. coli, S.aureus, and C.albicans. The MICs were 8 μM, 4 μM, and 32 μM. QUB-2982 also inhibited the growth of three kinds of human cancer cells: U251MG, PC-3, and H157. At the …
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Identification, isolation and bioactivity assessment of a bioactive peptide QUB-2339 from the skin secretion of the Hainan sucker frog, Amolops hainanensis
Many compounds in the skin secretion of the frogs are very significant for their survivals, which could protect them from both many diseases and attacks from microorganisms and predators. And the bioactive peptides in the secretions play very important and inevitable roles to these functions. Lots …
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Identification and functional assessment of a bioactive peptide QUB-2984 from the skin secretion of the red-eyed tree frog, Agalychnis callidryas
… included the isolation, identification, and bioactivity assessment of this bioactive peptide named QUB-2984. Agalychnis callidryas skin secretions were collected by stimulating the frogs’ skin. The sequence of QUB-2984 (GMWGTVFKGIKTVAKHLLPHVFSSQQS) was obtained by ‘shotgun’ cloning through …