Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 426 for “"bioactivity"”.
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Metabolic Bioactivity of Athrixia phylicoides
BACKGROUND: Insulin resistance is a major risk factor for the development of type 2 diabetes (T2D). It is characterized by insufficient response to secreted insulin in target tissues. In vitro studies demonstrated the ability of an aqueous extract of Athrixia phylicoides to increase glucose uptake …
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Structural Characterization And Bioactivity Of Cranberry Oligosaccharides
Complex carbohydrates from plant sources, such as the fruits of cranberry (Vaccinium macrocarpon Aiton), promote human health in a variety of ways. However, complete studies of carbohydrate function often hinge on a detailed understanding and thorough elucidation of the chemical structure. Several …
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The Bioactivity and Natural Products of Scottish Seaweeds
Seaweed has traditionally been used in Scotland and other countries both as food and for medicinal purposes, which has led to seaweed being investigated for their natural product content. Despite over 30 years of research, the majority of species found in Scotland have yet to have their chemistry …
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IMPLANT MATERIAL FUNCTIONALIZATION TO ENHANCE BIOACTIVITY IN ORTHOPAEDICS
… orthopaedic implant materials with enhanced bioactivity and improved implant-host interactions so as to reduce biological related implant failure.
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EFFECTS OF RED BLOOD CELLS ON NITRIC OXIDE BIOACTIVITY
Red blood cells (RBCs) as one of important cells in human blood vessel are abundant in hemoglobin (Hb). Hb has four heme ferrous sites for binding oxygen, nitric oxide (NO), carbon monoxide (CO) and other small molecules. NO as an endothelial derived relaxing factor is involved in many …
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Chemical aspects of saponin bioactivity and ovine photosensitization diseases
… from East Cape Manuka oil were subjected to a bioactivity evaluation against a range of bacterial and fungal organisms using the agar gel well diffusion technique. A possible structure-activity relationship amongst the synthesized saponins is discussed. The activity of triketone oil against two …
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The Metabolic Fate and Bioactivity of Anthocyanins in Humans
… formation of the metabolites. The cardiovascular bioactivity of anthocyanins may be linked to the antiinflammatory activity of their metabolites. IL-6 and VCAM-1 are cytokines and adhesion molecules integral to the initiation and progression of inflammation. In vitro, anthocyanin metabolites …
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Biocompatibility and Bioactivity of Calcium Silicate-based Dental Bioceramics
… were used to determine biocompatibility and bioactivity of tricalcium silicate-based materials:<br/><br/>1)Visual observations of cell<br/>2) Cell viability assays<br/>3)Immunocytochemistry<br/>4)Protein Biochemistry<br/>5)mRNA expression analysis<br/><br/>Visual observations demonstrated …
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Indicators of bioactivity and floral origin of New Zealand honeys
The hypothesis that NIR might be capable of discriminating one floral source from another was explored. No prior analysis of NIR for New Zealand honeys has been reported. A visual inspection of the NIR spectra of ten New Zealand honey types indicates that beech honeydew honey is significantly …
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Bioactivity and Cell-Mediated Targeting of Multistage Nanoporous Silicon Particles
<p>Progress in drug delivery approaches have not adequately translated into clinical advances in the diagnosis or treatment of inflammatory disorders (e.g., cancer). This disconnect is rooted in the inefficient delivery of imaging and therapeutic agents to the inflamed site upon systemic delivery. …
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Biopeptides from food by-products: Production, fractionation and bioactivity assessment
Es bien conocida la importante generación de residuos de la industria alimentaria y la importancia de llevar a cabo procesos y desarrollar técnicas y usos finales de dichos sub-productos con el fin de avanzar hacia una industria alimentaria sostenible. En esta Tesis Doctoral se plantean procesos de …
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Poly(glycoamidoamine)s: Understanding their Structure and Structure-Bioactivity Relationships
… from the endosome. In another study of structure-bioactivity relationship based on the degree of polymerization (DP) of poly(galactaramidopentaethylenetetramine) (<strong>G4</strong>), it was found that the increase in the DP of <strong>G4</strong> increases the toxicity of the polymers in the …
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Chemical characterisation of grapevine waste and bioactivity on cancer cell lines
… showed a dose and time dependent increase in bioactivity. In general K562 was found to be the least susceptible whilst MDA-MB-468 was the most susceptible. Morphological changes indicative of apoptosis were observed after 48 hour exposure. The highest bioactivity was for seed extracts which …
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Phytochemical Investigation and Bioactivity Assessment of Medicinal Plant from Northern Nigeria
Boswellia dalzielii (Burseraceae) has ethnopharmacological importance and is claimed to have anti-infection and immunomodulatory effects. In the Northern part of Nigeria, a region with a tropical dry climate, an aqueous infusion of this plant is used in the treatment of infections and tumours. The …
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In vitro studies of degradation and bioactivity of aliphatic polyesther composites
… diffusion for polymer degradation and bioactivity through nucleation and growth of apatite in simulated body fluid (SBF) solution. The objective of this study is to contribute to the understanding of the fundamentals in designing non-porous, solid materials for bone regeneration, from …
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Towards less hazardous chemicals : identifying chemical bioactivity through fish behavioral profiles.
Because most chemicals in commerce lack empirical toxicology information, innovative approaches are needed to identify substances presenting elevated hazards and risks to public health and the environment. When larval fish models are employed with automated tracking technologies, behavioral studies …
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A bioactivity peptide QUB2852 from the frog skin secretion of pelophylax nigromaculata
Due to the resistance of antibiotics, antimicrobial peptides (AMPs) become research hotspot. Majority of AMPs can disrupt the cell membrane of microorganisms, leading to the death of microorganisms. In this study, the AMP QUB-2852 was identified from the skin secretion of pelophylax nigromaculata …
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Assessing bioactivity of a peptide from the skin secretion of Rana amurensis
… haemolysis assays to determine the spectrum of bioactivity.<br/><br/>According to the results, QUB-1301 had no effect on contracting or relaxing the four kinds of rat smooth muscles including bladder, ileum, uterus and artery. Moreover, this peptide was eventually found to show activity against …
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Molecular Genetic Analysis of FGF23 Bioactivity in the Bone-Kidney Endocrine Axis
… However, the molecular mechanisms of FGF23 bioactivity in hormonal phosphate regulation are largely unknown. An experimental focus of this dissertation was to investigate the molecular mechanisms of FGF23-mediated phosphate regulation in the bone-kidney hormonal axis. To this end, the role …
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Integration and analysis of protein evolutionary relationships and small molecule bioactivity data
… database, a public repository of small molecule bioactivity measurements, with resources of protein evolutionary relationships, and exploit these new links to further our understanding of small molecule bioactivity. In order to link biological assays via the evolutionary relationships of their …
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