Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 106 for “"bioactive peptide"”.
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A novel bioactive peptide from the skin secretion of Rana chensinensis
… situation is severe, and antimicrobial peptides (AMPs) have become a new research topic for solving the issue of antibiotic resistance. In addition, AMPs have also shown remarkable anti-cancer effects. It is, therefore, important to look for promising alternatives to traditional …
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A novel bioactive peptide from the skin secretion of Hylarana nigrovittata
… active compounds contained in them. Many peptides from the skin secretions of amphibians have been found to have antimicrobial and enzyme inhibitory effects. In order to identify a new peptide from the skin secretion of the frog, Hylarana nigrovittata, and test its functions, several …
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QUB-2577: A Bioactive Peptide from Pickerel Frog (Rana palustris) Skin Secretion
… frogs contains a large number of antimicrobial peptides (AMPs) and they are considered as a promising source of antibiotic alternatives.<br/>In this thesis, the peptide QUB-2577 was identified by "shotgun" cloning of precursor-encoding cDNA derived from the skin secretion of Rana palustris. By …
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QUB-1073: a bioactive peptide from the skin secretion of Phyllomedusa rohdei
… study aimed to examine the characteristics of a bioactive peptide (QUB-1073) from the skin secretion of Phllomedusa rohdei and to determine the pharmacological activity on rat uterus and urinary bladder smooth muscle. <br/>A variety of biologically active peptides, including some new …
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A novel bioactive peptide from the defensive skin secretion of Phyllomedusa sauvagii
… activities. The research and exploitation of the peptides in amphibian skin secretions with antimicrobial or haemolytic activities has become increasingly popular. Many studies show that the antimicrobial peptides (AMPs) collected from amphibians have pharmacological and clinical …
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QUB-1985: a bioactive peptide from the frog skin secretion of Odorrana livida
… replace conventional antibiotics. Antimicrobial peptides (AMPs), possessing broad-spectrum antimicrobial activity, have raised great interests among medical field for its potential bioactivity against bacteria, fungi, viruses and cancer cells and its multi-target mechanisms. <br/><br/>In this …
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A bioactive peptide from the frog skin secretion of Pelophylax nigromaculatus GAPKGCWTKSYPPKPCS-NH2
In this study, we describe a synthesized peptide with C-terminally amidated, GAPKGCWTKSYPPKPCS-amide that contains a disulphide loop between Cys6 and Cys16 that is consistent with a Bowman–Birk type protease inhibitor, from the skin secretion of the frog Pelophylax nigromaculatus. The precursor was …
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QUB-1439: A bioactive peptide from the frog skin secretion of Hylarana guentheri
Antimicrobial peptides (AMPs) are a sufficient and diverse group of molecules that are derive from various invertebrate, plant and animal species. AMPs possess a variety of biological activity, such as anticancer, antivirus and so on. Nowadays, a growing number of AMPs are considered as promising …
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A bioactive peptide QUB-1370 from the frog skin secretion of Pelophylax nigromaculata
… of novel drugs to treat human diseases. Bioactive peptides from amphibian skin secretions have been demonstrated to have multiple biological activities, such as antimicrobial activity, anticancer activity and so on. Furthermore, some of the peptides have been proven as the promising …
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QUB-1957: a bioactive peptide from the frog skin secretion of Hylarana latouchii
… daily protection, especially the antimicrobial peptides. In this study, a cDNA library from lyophilised skin secretion of Hylarana latouchii was constructed, and molecular cloning of biosynthetic precursor-encoding cDNAs of QUB-1957 was performed. Subsequently, QUB-1957 was synthesised by Solid …
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QUB-2454: a bioactive peptide from the frog skin secretion of Phyllomedusa palliate
Antimicrobial peptides belonging to the dermaseptin family are mainly found in phyllomedusine frogs. These peptides not only possess potent antimicrobial activity but exhibit low toxicity against eukaryotic cells. In a recent study, potent antimicrobial activity was correlated with the conserved …
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QUB-1904: A Bioactive Peptide from the Frog Skin Secretion of Pelophylax esculentus
… inhibitory effect. <br/><br/>In this study, a bioactive peptide, QUB-1904, was discovered from skin secretion of Pelophylax esculentus by shotgun cloning of a novel biosynthetic precursor encoded cDNA smoothly. Through the bioinformatic analysis, the amino-acid sequences of mature peptide was …
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QUB-3005, a bioactive peptide from the defensive skin secretion of Rana amurensis
… amines, steroids, complex alkaloids, and peptides. In the latter class of molecules, a large number of peptide antibiotics has been isolated and characterised from different amphibian species. Particularly, antimicrobial peptides (AMPs) are considered as excellent candidates for …
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A bioactive peptide, QUB-2048, from the defensive skin secretion of Phyllomedusa tomopterna
… skin secretion is deemed as a reservoir of bioactive compounds and antimicrobial peptides (AMPs) are among the most attractive of these. Due to antibiotic resistance and the eager need of developing new types of anti-infective drugs, such peptides are considered as an alternative therapeutic …
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QUB-2614: a bioactive peptide from the defensive skin secretion of Odorrana schmackeri
… compounds, such as anti-microbial peptides (AMPs) and anticancer peptides (ACPs), which are used by biomedical researchers as a source of potential novel drug leads or pharmacological tools.<br/><br/>In this thesis, an AMP was identified in the skin secretion of Odorrana schmackeri …
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QUB-1453: A Bioactive Peptide from the Defensive Skin Secretion of Rana amurensis
… is one of the richest sources for antimicrobial peptides (AMPs) which have potent bioactivity and pharmaceutical value for new drug development. In this thesis, QUB-1452, an AMP, was isolated and characterised from the skin secretion of Rana amurensis. The peptide is composed of 13 amino acid …
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A bioactive peptide from the defensive skin secretion of <i>Odorrana versabilis</i>
The skin of amphibians is rich in bioactive substances among which are those called bioactive peptides. The bioactive peptides could play a key role in new drug development. In this thesis, a bioactive peptide named QUB-1966, was isolated and characterised from the skin secretion of the Chinese …
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QUB-2791: Identification of novel bioactive peptide from the Agalychnis annae skin secretions
… with other small molecule drugs, Antibacterial peptides (AMPs) found in the secretions of amphibians have broad-spectrum antibacterial activity. In addition, AMP and antibiotics have different killing mechanisms, therefore, AMP may be promising for solving the antibiotic resistance.<br/><br/>In …
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QUB-2825: A novel bioactive peptide from the skin secretion of Phyllomedusa hypochondrialis
… skin secretions contain large amounts of bioactive molecules, especially antimicrobial peptides (AMPs), which has drawn great attention of researchers. Due to their potential as alternative candidates for the treatment of multi-drug resistance microbes. The dermaseptins consist of a …
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A novel bioactive peptide QUB-2022 from the skin secretion of Phyllomedusa bicolor
The antimicrobial peptide (AMP) is a type of small molecular peptides that are produced by the body against infection. They are commonly considered as a fundamental component of innate immunity and have been extensively discovered in the insects and other non-vertebrate organisms. Amphibian skin …
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