Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"binucleation"”.
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Prospective Isolation And Characterization Of Mononucleated And Binucleated Cardiomyocytes
… revealed that during the neonatal period, binucleation is associated with the termination of a proliferation-associated gene expression program in exchange for a mature cardiomyocyte gene expression program. Our data also suggested that an E2f/Rb transcriptional network is central to the …
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An Evaluation of the Occurrence of Micronuclei and other Nuclear Abnormalities in Fishes from the Great Lakes Basin, United States
… (NA) such as notching, lobes, blebbing, and binucleation are observed from the nuclear membrane and are indicators for mutagenic contamination. The micronucleus assay was incorporated to assess genotoxic and mutagenic contamination among sites, species, and season from fish collected from 8 …
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Characterization of the cardiogenesis of embryonic stem cells
… overlaying collagen gel impeded cell elongation. Binucleation. characteristic of maturing cardiomyocytes, was reduced with soluble collagen supplement and nanoscale topography and was associated with an increase in cytokinesis. Both nanoscale topography and microcontact printing resulted in …
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DOES CALCIUM INFLUX THROUGH T-TYPE CALCIUM CHANNEL INDUCE CARDIOMYOCYTE PROLIFERATION?
… T-type calcium channel could partially prevent binucleation from happening and stop cardiomyocytes withdrawal from cell cycle. Mononucleated cardiomyocyte is still able to proliferate. Hence, mononucleated cardiomyocytes in adult still have potential to proliferation because these cardiomyoctes …
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Cardiomyocyte Cell Cycle, Renewal and Isolation
Heart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. In paper I, the focus is on the …