Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1094 for “"binding protein"”.
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Possible Interacting Proteins for Retinol Binding Protein and Cellular Retinol Binding Protein
… in the circulatory system attached to Retinol Binding Protein (RBP) and its transport into the cell is mediated by the RBP receptor STRA6. Inside the cell, retinol binds to cellular Retinol Binding Protein (CRBP) and can be converted to retinoic acid, which can then act as a regulator of …
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The guanylate binding protein-1
… and tumour angiogenesis. The human guanylate binding protein-1 (GBP-1) is a protein of the family of large GTPases. GBP-1 is characterized by a high turnover GTPase activity. Previous work showed that GBP-1 mRNA expression is induced by IC in EC and that GBP-1 is the specific mediator of the …
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Identification of binding protein with kinesin18B
… This transport depends on the activity of motor proteins that interact with microtubules. Most kinesins move cargoes outwards toward the cytoplasmic membrane. Members of the kinesin family have been implicated in vesicle and organelle transport, spindle and chromosome motility during meiosis and …
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The DNA Binding Protein Lsr2 from Mycobacterium tuberculosis
Lsr2 is a small, basic DNA binding protein that is highly conserved in mycobacteria and related actinomycetes. Lsr2 is essential for growth in Mycobacterium tuberculosis and previous studies have shown that Lsr2 is involved in down-regulating a wide range of genes involved in cell wall synthesis …
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Functional characterization of the RNA binding protein RALY
… these events produce a high number of different proteins that form the basis for the high variety of cells. The RNAbinding proteins (RBPs) play crucial roles in this variability by regulating many steps of biological processes regarding RNA metabolism. The heterogeneous nuclear ribonucleoproteins …
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Design of a high-affinity carbohydrate binding protein
Kohlenhydrat-Protein Interaktionen sind in der Natur weitverbreitet. Sie stellen die Grundlage für viele biologische Prozesse dar, wie zum Beispiel Immunantworten, Wundheilung und Infektionsprozesse von pathogenen Viren oder Bakterien mit einem Wirt wie dem Menschen. Neben der Infektion von …
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Interdomain Repression in the Enhancer Binding Protein NorR
… by NorR, a member of the bacterial Enhancer Binding Protein (bEBP)-family that activates σ54-dependent transcription of the norVW genes under conditions of nitrosative stress. Binding of NorR to three conserved enhancer sites upstream of the norVW promoter is essential for transcriptional …
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Post-transcriptional coordination by an RNA-binding protein
RNA-binding proteins can regulate the stability, localization, and translation of their target mRNAs. Post-transcriptional regulation can orchestrate dynamic changes in gene expression, and can coordinate multiple cellular processes in response to various stimuli. Filamentous growth in …
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Characterizing interactions between cAMP responsive element binding protein 1 and methyl-CpG-binding protein 2 as a potential transcriptional activation complex
… activity is controlled by many types of DNA binding proteins. In addition to transcription factors that activate transcription by recruitment of RNA polymerase II, there are proteins like methyl-CpG-binding protein 2 (MeCP2). MeCP2 regulates transcription by binding to methylated DNA. MeCP2 …
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Regulation of Memory by the Actin-Binding Protein Cofilin
… This remodeling is regulated by the actin binding protein cofilin, but its role in learning and memory remains unclear. Physiologically relevant manipulations of cofilin activity in vivo provide new opportunities for examining its function in learning and memory. Therefore, in this thesis, …
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Regulation and function of the RNA-binding protein CELF1
… An important regulator of mRNA decay is the RNA binding protein CUGBP1 and Etr3 Like Factor 1 (CELF1). CELF1 binds to a GU-rich element (GRE) harbored in target transcripts and promotes their rapid decay through the recruitment of RNA decay enzymes. The work presented in this thesis focused on …
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A Putative Cytosolic Saxitoxin Binding Protein in Frog Myocardium
Approximately 20% of the protein in sarcolemma vesicles prepared from the hearts of the North American frog Rana pipiens pipiens is solubilized by a 96 hour dialysis of the vesicles against a low ionic strength solution of ethylene-diaminetetraacetic acid (EDTA) at pH 8.5. All of the polypeptides …
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Characterization of Small Molecules Inhibiting the RNA Binding Protein HuR
… (embryonic lethal abnormal vision) family of RNA binding proteins, selectively binds to AREs (AU-rich elements) and mainly stabilizes ARE-containing mRNAs, e.g. TNFα, VEGF, c-FOS, favoring specific protein translation. TNFα mRNA is one of the most important target mRNA of HuR since the protein …
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THE RNA-BINDING PROTEIN LRP1 MEDIATES FLOWERING TIME IN ARABIDOPSIS
… pathway. We show that LATE FLOWERING RNA-BINDING PROTEIN 1 (LRP1), an RNA-binding protein, promotes flowering through modulating <i>FLC</i> mRNA levels. <i>LRP1</i> mRNA is highly expressed in shoot apices and young leaves, while its protein is localized in the cytoplasm and nucleus. …
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A 450K arsenite-binding protein of the rabbit liver cytosol
… cytosolic macromolecules. The specifics of this binding and its role in arsenic toxicity have never been fully examined. This dissertation concentrated on determining the species of inorganic arsenic which binds to liver cytosolic proteins, the specific proteins involved and the characteristics …
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DNA methylation detection using an engineered methyl-CpG-binding protein
… of such testing to more patients. Methyl-CpG-binding domain (MBD) proteins bind specifically to methylated DNA sequences, and many assays have been developed that use these proteins in methylation profiling of DNA. The wild-type proteins in the MBD family bind specifically to symmetrically …
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Functional Studies of Penicillin-binding Protein 1 in Bacillus subtilis
The penicillin-binding proteins (PBPs) synthesize and modify peptidoglycan (PG), the main structural element of the bacterial cell wall. PBPs and PG synthesis are highly conserved in all bacteria and both have been important targets for antibiotic and antibacterial development. In the Gram positive …
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Transferrin binding protein B structure, function, and export in Neisseria gonorrhoeae
… is sequestered in the host by iron-binding proteins, such as lactoferrin and transferrin. Neisseria gonorrhoeae utilizes transferrin as an iron source and its iron acquisition system is composed of two transferrin binding proteins: TbpA and TbpB. TbpA is a TonB-dependent, outer …
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