Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"biliary epithelial cells"”.
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Mechanisms of methylenedianiline toxicity to rat biliary epithelial cells
… polyurethanes and epoxy resins, rapidly injures biliary epithelial cells (BEC) of rats in vivo. DAPM also increases biliary inorganic phosphate and glucose, suggesting that DAPM loosens hepatic tight junctions. Early ultrastructural alterations in BEC mitochondria, however, suggested a possible …
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Investigating the role of primary cilia loss in intrahepatic cholangiocarcinoma
… sensory organelles which protrude from the epithelial cells lining bile ducts (cholangiocytes), where they serve as sensors of bile composition, flow and osmolality. PC malformation has been reported in cholangiocarcinoma (CCA), a neoplasia that originates from these biliary epithelial …
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ROLE OF NATURAL KILLER CELLS IN THE PATHOGENESIS OF PRIMARY BILIARY CHOLANGITIS
Background: Primary biliary cholangitis (PBC) is the most prevalent autoimmune liver disease and involves the selective destruction of small intrahepatic biliary epithelial cells (BECs), potentially leading to biliary cirrhosis and liver transplantation, if left untreated. As of now, …
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Vacuolation, proliferation and neoplasia in the liver of Boston Harbor winter flounder (Pseudopleuronectes americanus)
… lesions of all types. These vacuolated cells were first seen in the center of the hepatic tubule, as vacuolated preductular biliary epithelial cells. Later, cells of the entire hepatic tubule were vacuolated. Foci of vacuolated cells were visible grossly, and often contained or were …
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Snail1-mediated Gene Repression Links EMT to Enhanced Biliary Epithelial Cell Survival and Lung Epithelial Cancer Cell Migration
… understanding of the underlying mechanisms. Epithelial-mesenchymal-transition (EMT) is a naturally occurring and strictly regulated trans-differentiation process essential for tissue morphogenesis during early embryonic development. Recent studies suggest that aberrant reactivation of EMT in …
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Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex
… region with no known enzymatic function. Primary biliary cirrhosis (PBC) is a chronic autoimmune liver disease in which inflammatory infiltration of the intrahepatic bile ducts leads to damage of the biliary epithelial cells followed by fibrosis, cirrhosis and ultimately liver failure. The disease …