Global ETD Search
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Showing 1 to 6 of 6 for “"bicuspid aortic valve"”.
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Collagen structure within aneurysm tissue in bicuspid aortic valve patients
Aortic aneurysms pose a substantial clinical problem, especially in individuals with bicuspid aortic valve (BAV) disease, as aneurysm formation is 50% more common in these populations. Although the exact cause of aortic aneurysms in BAV patients is still unknown, a growing body of research points …
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Investigation into the genetic nature of familial congenital bicuspid aortic valve
Bicuspid aortic valve (BAV) affects approximately 1% of the general population and its etiology remains unknown. Based on literature reports, we hypothesized that congenital BAV (cBAV) was a developmental defect inherited as an autosomal dominant trait with variable penetrance. We evaluated the …
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Evaluation of Recurrence Risks For Left-Sided Cardiac Lesions
… that hypoplastic left heart syndrome (HLHS), aortic valve stenosis with or without bicuspid aortic valve (AS/BAV) and coarctation of the aorta (CoA) occur in families more commonly with each other than with any other congenital heart defect (CHD). Genetic counseling for CHDs is currently based …
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Identifying Regional DNA Methylation Patterns in the Human Aorta in Health and Disease
The prevalence of a congenital bicuspid aortic valve (BAV) is 0.5 to 1% of the population. The condition arises from the fusion of two aortic valve leaflets and is commonly associated with progressive dilation of the aorta (aortopathy) which can lead to sudden and life-threatening complications …
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Imaging microcalcium in thoracic aortic disease
… complications occur, such as stroke or aortic dissection. Current management strategies focus on preventative interventions which can include high-risk surgery. However, identifying those who are most appropriate for such interventions is challenging. Deposition of calcium crystals …
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Spectrum Of Causes Of Isolated Aortic Regurgitation At A South African Public Sector Tertiary Care Institution
BACKGROUND Aortic Regurgitation (AR) is due to primary abnormalities of the aortic valve, peri-valvular apparatus and/or the aortic root and the ascending aorta. Whereas the etiology and mechanisms of AR are relatively well described in Europe and North America, little information exists about …