Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"bicoid"”.
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A novel statistical signal processing approach for analysing high volatile expression profiles.
… Network (SN) in Drosophila melanogaster and the bicoid gene (bcd) as the critical input of this network are targeted to study. The first contribution of this research is to introduce a new noise filtering and signal processing algorithm based on Singular Spectrum Analysis (SSA) for extracting the …
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Evolution of caudal translational repression in higher insects
Der anterior lokalisierte Entwicklungsfaktor bicoid (bcd) steuert the translationale Repression von caudal (cad) in Drosophila Embryos. Das bcd Gen kommt im Gegensatz zu cad nur in einer abgeleiteten Gruppe von Diptera vor. Die Expression von cad in anderen Insektenarten muss daher auf andere Weise …
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Investigating processing body condensation, material properties and function during early Drosophila development
… state of P bodies allows for the storage of bicoid, a key maternal transcript needed for embryonic development. Using pharmacological disruption and live imaging, I show that large scale cytoplasmic reorganisation causes P body dispersal during the oocyte to embryo transition to release the …
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Investigation of Interactions between Homeodomain Proteins and DNA
… Fluoreszenz und des Circulardichroismus von Bicoid- (Bcd), Ultrabithorax- (Ubx) und Engrailed- (En) Homeodomänen hat gezeigt, dass die Bindung dieser Proteine an doppelsträngige 15 bp Oligonukleotide Veränderungen in der Sruktur der Homeodomänen hervorruft. Diese Veränderungen sind …
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Genome-wide prediction of developmental enhancers and analysis of evolutionary plasticity in Drosophila
… DNA sequences. The transcription factors Bicoid (BCD), Caudal (CAD), Hunchback (HB), Kruppel (KR), and Knirps (KNI) are crucial in patterning the anterior-posterior axis of the embryo by acting at very early stages of Drosophila development. In prior studies, functional tests of 37 …
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Investigating the regulation of processing bodies in Drosophila melanogaster oocytes
… the maternally deposited axis-determining mRNA, bicoid (bcd). In the mature oocytes, bcd is associated with P bodies and remains translationally silent. Upon egg activation, P bodies disassemble, releasing bcd into the cytoplasm where it associates with ribosomes and is translated. P body …
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Investigating the function and mechanistic control of processing bodies in early Drosophila melanogaster development
… and association with the anterior determinant, *bicoid* (*bcd*) mRNA, throughout oogenesis. When the oocyte reaches maturity, virtually all *bcd* is found in P-bodies. At this point in developmental time, *bcd* is tightly localised at the anterior margin, translationally repressed, and stable for …