Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"bi-specific antibody"”.
-
Development and Characterization of A Bi-Specific Antibody Targeting Hla-A2/Pr1
… of a T cell receptor-like monoclonal antibody (h8F4) that targets PR1/HLA-A2 and eliminates AML xenografts by antibody-dependent cellular cytotoxicity (ADCC) following repeat dosing. To improve the potency of h8F4, we have developed a bi-specific T cell-engaging antibody that targets …
-
Autogramin-2, a synthetic sterol, inhibits T cell adhesion and effector function
… is a key regulator of T cell immunity as it stabilises immune synapses, thus supporting effector T cell function. Recent publications suggest that increasing plasma membrane cholesterol content boosts anti-viral and anti-cancer immunity in T cells. Inhibition of cholesterol transport from the …