Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"beta-hexosaminidase"”.
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PLASMA MEMBRANE ASSOCIATED GLYCOHYDROLASES: KINETICS PARAMETER CHARACTERIZATION AND BIOLOGICAL FUNCTION
… assay) method able to measure the activity of beta-galactosidase, CBE sensitive beta-glucosidase, GBA2 beta-glucosidase, SMase and beta-hexosaminidases, enzymes working directly at the plasma membrane level using MUB derivates as substrate. Afterwards we applied this assays in order to study …
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Partial Molecular and Biochemical Characterization of a Sandhoff Mouse Model
… HEXB gene, which results in a deficiency of the ‘beta-hexosaminidase A’ enzyme for which it codes; however, a better understanding of the pathology is needed. The objective of this study was, therefore, to better characterize SD to improve our understanding of the disease. This study took two …
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The role of heterozygous lysosomal storage disorder alleles as risk factors for dementia
… is characterised by extracellular amyloid beta plaques and intraneuronal tau tangles. While it is not fully understood why these pathological hallmarks develop, several biological systems are believed to be involved. Of these, lysosomal network dysfunction is an increasingly recognised …