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Showing 1 to 2 of 2 for “"beta-hairpin peptides"”.

  1. Observing the unfolding transition of [beta]-hairpin peptides with nonlinear infrared spectroscopy

    … the time scale of the transition. Single domain peptides are excellent model systems that reduce the size and complexity of the problem, while maintaining the essential physical interactions. In this thesis, P-hairpin peptides are used as model systems for studying P-sheet secondary structure. …

    mit Repository record for Observing the unfolding transition of [beta]-hairpin peptides with nonlinear infrared spectroscopy (opens in a new tab)

  2. Incorporation of Cα,α-Disubstituted Amino Acids into Model Peptide Systems: Conformational Analysis and Possible Applications as Therapeutic Agents

    … contribute to β-sheet formation and stability. Peptides that autonomously form β-sheets are ideal models to study principles of protein folding and design. Gellman and coworkers first introduced an automonously folded β-hairpin (H-Arg-Tyr-Val-Glu-Val-Yyy-Xxx-Orn-Lys-Ile-Leu-Gln-NH2) that …

    lsu-thes Repository record for Incorporation of Cα,α-Disubstituted Amino Acids into Model Peptide Systems: Conformational Analysis and Possible Applications as Therapeutic Agents (opens in a new tab)