Global ETD Search
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Showing 1 to 1 of 1 for “"beta-arrestin recruitment"”.
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Biased Constitutive Activity in the Uveal Melanoma Oncogene CYSLTR2 is Unique in CYSLTR2 Germline and Pan-Cancer Human Variome
… However, CysLTR2-L129Q only poorly recruits β-arrestin as shown by a bioluminescence resonance energy transfer 2 (BRET2) based β-arrestin recruitment assay. Using a modified Slack-Hall operational model, we quantified the constitutive activity for both pathways and conclude that CysLTR2-L129Q …