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Showing 1 to 1 of 1 for “"beta-Sekretase"”.
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Reconstituting APP and BACE in proteoliposomes to characterize lipid requirements for β-secretase activity
… protein (APP) may lead to the formation of the Abeta peptide, the major constituent of amyloid plaques in Alzheimer`s disease. The full-length APP is a substrate for at least 2 different (alpha and beta) proteases ("secretases"). The beta-secretase, BACE, cleaves APP in the first step …